Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
1R29CA070335-01
Application #
2114243
Study Section
Metabolic Pathology Study Section (MEP)
Project Start
1996-08-01
Project End
2001-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Fox Chase Cancer Center
Department
Type
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19111
Calvert, Paula M; Frucht, Harold (2002) The genetics of colorectal cancer. Ann Intern Med 137:603-12
Cheng, Kunrong; Chen, Ying; Zimniak, Piotr et al. (2002) Functional interaction of lithocholic acid conjugates with M3 muscarinic receptors on a human colon cancer cell line. Biochim Biophys Acta 1588:48-55
Yang, W L; Frucht, H (2001) Activation of the PPAR pathway induces apoptosis and COX-2 inhibition in HT-29 human colon cancer cells. Carcinogenesis 22:1379-83
Yang, W L; Frucht, H (2000) Cholinergic receptor up-regulates COX-2 expression and prostaglandin E(2) production in colon cancer cells. Carcinogenesis 21:1789-93
Frucht, H; Jensen, R T; Dexter, D et al. (1999) Human colon cancer cell proliferation mediated by the M3 muscarinic cholinergic receptor. Clin Cancer Res 5:2532-9