Restoration of Integrin Function in Cml by Interferon

Bhatia, Ravi

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Cancer Institute (NCI)
• Type: First Independent Research Support & Transition (FIRST) Awards (R29)
• Project #: 1R29CA074455-01
• Application #: 2012432
• Study Section: Hematology Subcommittee 2 (HEM)
• Project Start: 1996-09-15
• Project End: 2001-08-31
• Budget Start: 1996-09-15
• Budget End: 1997-08-31
• Support Year: 1
• Fiscal Year: 1996

Institution

• Name: City of Hope National Medical Center
• City: Duarte
• State: CA
• Country: United States
• Zip Code: 91010

Publications

Bhatia, R; Munthe, H A; Williams, A D et al. (2000) Chronic myelogenous leukemia primitive hematopoietic progenitors demonstrate increased sensitivity to growth factor-induced proliferation and maturation. Exp Hematol 28:1401-12

Bhatia, R; Munthe, H A; Verfaillie, C M (1999) Role of abnormal integrin-cytoskeletal interactions in impaired beta1 integrin function in chronic myelogenous leukemia hematopoietic progenitors. Exp Hematol 27:1384-96

Bhatia, R; Munthe, H A; Verfaillie, C M (1998) Tyrphostin AG957, a tyrosine kinase inhibitor with anti-BCR/ABL tyrosine kinase activity restores beta1 integrin-mediated adhesion and inhibitory signaling in chronic myelogenous leukemia hematopoietic progenitors. Leukemia 12:1708-17

Bhatia, R; Verfaillie, C M (1998) Inhibition of BCR-ABL expression with antisense oligodeoxynucleotides restores beta1 integrin-mediated adhesion and proliferation inhibition in chronic myelogenous leukemia hematopoietic progenitors. Blood 91:3414-22