Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
5R29DA007327-05
Application #
2119804
Study Section
Drug Abuse Clinical and Behavioral Research Review Committee (DACB)
Project Start
1991-07-01
Project End
1997-06-30
Budget Start
1995-07-15
Budget End
1997-06-30
Support Year
5
Fiscal Year
1995
Total Cost
Indirect Cost
Name
University of North Carolina Chapel Hill
Department
Psychology
Type
Schools of Arts and Sciences
DUNS #
078861598
City
Chapel Hill
State
NC
Country
United States
Zip Code
27599
Picker, M J; Cook, C D (1997) Discriminative stimulus effects of opioids in pigeons trained to discriminate fentanyl, bremazocine and water: evidence of pharmacological selectivity. Behav Pharmacol 8:160-73
Hughes, C E; Dykstra, L A (1997) Antagonism of the response rate-decreasing effects of meperidine and morphine by beta-funaltrexamine and naltrexone in squirrel monkeys. Drug Alcohol Depend 45:197-206
Smith, M A; Pitts, R C; Picker, M J (1997) Tolerance and cross tolerance to the accuracy- and rate-decreasing effects of mu opioids in rats responding under a fixed-consecutive-number schedule. Drug Alcohol Depend 46:19-30
Hughes, C E; Habash, T; Dykstra, L A et al. (1996) Discriminative-stimulus effects of morphine in combination with alpha- and beta-noradrenergic agonists and antagonists in rats. Pharmacol Biochem Behav 53:979-86
Picker, M J; Benyas, S; Horwitz, J A et al. (1996) Discriminative stimulus effects of butorphanol: influence of training dose on the substitution patterns produced by Mu, Kappa and Delta opioid agonists. J Pharmacol Exp Ther 279:1130-41
Negus, S S; Morgan, D; Cook, C D et al. (1996) Effects of the delta opioid against BW373U86 in pigeons trained to discriminate fentanyl, bremazocine and water in a three-choice drug discrimination procedure. Psychopharmacology (Berl) 126:199-205
Morgan, D; Picker, M J (1995) Discriminative stimulus effects of the 5HT1A agonist 8-OH-DPAT: attenuation by mu but not by kappa opioids. Psychopharmacology (Berl) 122:336-45
Picker, M J (1994) Kappa agonist and antagonist properties of mixed action opioids in a pigeon drug discrimination procedure. J Pharmacol Exp Ther 268:1190-8
Picker, M J; Yarbrough, J; Hughes, C E et al. (1993) Agonist and antagonist effects of mixed action opioids in the pigeon drug discrimination procedure: influence of training dose, intrinsic efficacy and interanimal differences. J Pharmacol Exp Ther 266:756-67
Picker, M J; Craft, R M; Negus, S S et al. (1992) Intermediate efficacy mu opioids: examination of their morphine-like stimulus effects and response rate-decreasing effects in morphine-tolerant rats. J Pharmacol Exp Ther 263:668-81