Abstract

Evoked otoacoustic emissions (OAE) are produced by active processes in the inner ear by interactions with external tones, and provide important data for modeling the mechanisms of hearing. The existence of spontaneous otoacoustic emissions (SOAE), while themselves apparently having no direct role in hearing, pose a problem that any realistic model of the cochlea must account for. A model of the auditory periphery is proposed to account for the large body of data on OAEs, which will have a profound impact on the hearing research carried out by this Purdue group. The model connects apparently disparate phenomenon in a mathematically rigorous fashion, and thus guides the scope of specific experiments and suggests new experiments. The models have significance for the clinical use of SOAEs and evoked OAEs in hearing assessment, particularly for distortion product OAEs, since the question of understanding the underlying mechanisms has an impact on how results should be interpreted clinically. It is expected that the model will play an important role on the group's future research in clinical applications of evoked OAEs.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute on Deafness and Other Communication Disorders (NIDCD)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
7R29DC003094-02
Application #
2733694
Study Section
Hearing Research Study Section (HAR)
Project Start
1997-07-01
Project End
2002-06-30
Budget Start
1998-07-01
Budget End
1999-06-30
Support Year
2
Fiscal Year
1998
Total Cost
Indirect Cost

  Institution

Name
University of Mississippi
Department
Miscellaneous
Type
Schools of Arts and Sciences
DUNS #
City
University
State
MS
Country
United States
Zip Code
38677

  Publications

Dhar, Sumitrajit; Long, Glenis R; Talmadge, Carrick L et al. (2005) The effect of stimulus-frequency ratio on distortion product otoacoustic emission components. J Acoust Soc Am 117:3766-76
Shera, Christopher A; Tubis, Arnold; Talmadge, Carrick L (2004) Do forward- and backward-traveling waves occur within the cochlea? Countering the critique of Nobili et al. J Assoc Res Otolaryngol 5:349-59
Withnell, Robert H; Shaffer, Lauren A; Talmadge, Carrick L (2003) Generation of DPOAEs in the guinea pig. Hear Res 178:106-17
Dhar, Sumitrajit; Talmadge, Carrick L; Long, Glenis R et al. (2002) Multiple internal reflections in the cochlea and their effect on DPOAE fine structure. J Acoust Soc Am 112:2882-97
Tubis, A; Talmadge, C L; Tong, C et al. (2000) On the relationships between the fixed-f1, fixed-f2, and fixed-ratio phase derivatives of the 2f1-f2 distortion product otoacoustic emission. J Acoust Soc Am 108:1772-85
Tubis, A; Talmadge, C L; Tong, C (2000) Modeling the temporal behavior of distortion product otoacoustic emissions. J Acoust Soc Am 107:2112-27
Talmadge, C L; Tubis, A; Long, G R et al. (2000) Modeling the combined effects of basilar membrane nonlinearity and roughness on stimulus frequency otoacoustic emission fine structure. J Acoust Soc Am 108:2911-32
Shera, C A; Talmadge, C L; Tubis, A (2000) Interrelations among distortion-product phase-gradient delays: their connection to scaling symmetry and its breaking. J Acoust Soc Am 108:2933-48
Talmadge, C L; Long, G R; Tubis, A et al. (1999) Experimental confirmation of the two-source interference model for the fine structure of distortion product otoacoustic emissions. J Acoust Soc Am 105:275-92
Talmadge, C L; Tubis, A; Long, G R et al. (1998) Modeling otoacoustic emission and hearing threshold fine structures. J Acoust Soc Am 104:1517-43

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