This study is designed to investigate the aerodynamic characteristics of the upper vocal tract in 520 normally speaking subjects and between 300 and 500 subjects with palatal clefts ranging in age from five to 29 years. Data on the size of the velopharyngeal orifice and pressure-flow timing characteristics during speech production will be collected along with measurements of pharyngeal-nasal airway resistance and oral-nasal breathing ratios. Normal children will be studied longitudinally during the period of adenoid atrophy. Children with cleft palates who exhibit borderline speech characteristics or who have pharyngeal flaps during the course of the study also will be followed longitudinally over time. Measurements of the speakers with and without clefts will be compared at the different ages, and the changes occurring as a function of age will be evaluated. This study represents the first large-scale comparative investigation of aerodynamic characteristics from early childhood through adulthood in speakers without palatal clefts as they compare to speakers with clefts and the first study to assess aerodynamic changes over time in cleft speakers. These data are vital to improving our criteria for the clinical interpretation of aerodynamic measurements leading to decisions about clinical management. The longitudinal data, in particular, should be of special value to speech clinicians and surgeons in determining the type and timing of treatment. Finally, insights relative to the effects of normal growth and to adaptations of cleft lip and palate speakers with marginal or impaired speech with or without pharyngeal flaps will be obtained.

Agency
National Institute of Health (NIH)
Institute
National Institute of Dental & Craniofacial Research (NIDCR)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
1R29DE010175-01A1
Application #
3462429
Study Section
Oral Biology and Medicine Subcommittee 1 (OBM)
Project Start
1993-01-01
Project End
1997-12-31
Budget Start
1993-01-01
Budget End
1993-12-31
Support Year
1
Fiscal Year
1993
Total Cost
Indirect Cost
Name
University of Pittsburgh
Department
Type
Schools of Dentistry
DUNS #
053785812
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213
Young, L H; Zajac, D J; Mayo, R et al. (2001) Effects of vowel height and vocal intensity on anticipatory nasal airflow in individuals with normal speech. J Speech Lang Hear Res 44:52-60
Zajac, D J (2000) Pressure-flow characteristics of /m/ and /p/ production in speakers without cleft palate: developmental findings. Cleft Palate Craniofac J 37:468-77
Zajac, D J; Fornataro-Clerici, L; Roop, T A (1999) Aerodynamic characteristics of tracheostomy speaking valves: an updated report. J Speech Lang Hear Res 42:92-100
Zajac, D J (1998) Effects of a pressure target on laryngeal airway resistance in children. J Commun Disord 31:201-12;quiz 212-3
Zajac, D J; Mayo, R; Kataoka, R (1998) Nasal coarticulation in normal speakers: a re-examination of the effects of gender. J Speech Lang Hear Res 41:503-10
Zajac, D J (1997) Velopharyngeal function in young and older adult speakers: evidence from aerodynamic studies. J Acoust Soc Am 102:1846-52