Agency
National Institute of Health (NIH)
Institute
National Institute of Dental & Craniofacial Research (NIDCR)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
3R29DE011553-01S1
Application #
2132909
Study Section
Special Emphasis Panel (ZDE1-YS (21))
Project Start
1995-09-01
Project End
2000-06-30
Budget Start
1995-09-01
Budget End
1996-06-30
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Texas A&M Baylor College of Dentistry
Department
Other Basic Sciences
Type
Schools of Dentistry
DUNS #
City
Dallas
State
TX
Country
United States
Zip Code
75246
Cutler, Christopher W; Iacopino, Anthony M (2003) Periodontal disease: links with serum lipid/ triglyceride levels? Review and new data. J Int Acad Periodontol 5:47-51
Iacopino, A M; Cutler, C W (2000) Pathophysiological relationships between periodontitis and systemic disease: recent concepts involving serum lipids. J Periodontol 71:1375-84
Chu, X; Newman, J; Park, B et al. (1999) In vitro alteration of macrophage phenotype and function by serum lipids. Cell Tissue Res 296:331-7
Cutler, C W; Machen, R L; Jotwani, R et al. (1999) Heightened gingival inflammation and attachment loss in type 2 diabetics with hyperlipidemia. J Periodontol 70:1313-21
Boltchi, F E; Rees, T D; Iacopino, A M (1999) Cyclosporine A-induced gingival overgrowth: a comprehensive review. Quintessence Int 30:775-83
Doxey, D L; Cutler, C W; Iacopino, A M (1998) Diabetes prevents periodontitis-induced increases in gingival platelet derived growth factor-B and interleukin 1-beta in a rat model. J Periodontol 69:113-9
Doxey, D L; Nares, S; Park, B et al. (1998) Diabetes-induced impairment of macrophage cytokine release in a rat model: potential role of serum lipids. Life Sci 63:1127-36
Dill, R E; Iacopino, A M (1997) Myofibroblasts in phenytoin-induced hyperplastic connective tissue in the rat and in human gingival overgrowth. J Periodontol 68:375-80
Iacopino, A M; Doxey, D; Cutler, C W et al. (1997) Phenytoin and cyclosporine A specifically regulate macrophage phenotype and expression of platelet-derived growth factor and interleukin-1 in vitro and in vivo: possible molecular mechanism of drug-induced gingival hyperplasia. J Periodontol 68:73-83
Shih, S D; Rees, T D; Miller, E G et al. (1996) The effects of platelet-derived growth factor-BB and insulin-like growth factor-1 on epithelial dysplasia. J Periodontol 67:1224-32

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