Growth Factor Regulation of Cranial Suture Morphogenesis

Opperman, Lynne A.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Dental & Craniofacial Research (NIDCR)
• Type: First Independent Research Support & Transition (FIRST) Awards (R29)
• Project #: 1R29DE011978-01
• Application #: 2133320
• Study Section: Oral Biology and Medicine Subcommittee 1 (OBM)
• Project Start: 1996-09-01
• Project End: 1996-12-31
• Budget Start: 1996-09-01
• Budget End: 1996-12-31
• Support Year: 1
• Fiscal Year: 1996

Institution

• Name: University of Virginia
• Department: Surgery
• Type: Schools of Medicine
• DUNS #: 001910777
• City: Charlottesville
• State: VA
• Country: United States
• Zip Code: 22904

Publications

Shibazaki-Yorozuya, Reiko; Wang, Qian; Dechow, Paul C et al. (2012) Changes in biomechanical strain and morphology of rat calvarial sutures and bone after Tgf-?3 inhibition of posterior interfrontal suture fusion. Anat Rec (Hoboken) 295:928-38

Adab, K; Sayne, J R; Carlson, D S et al. (2002) Tgf-beta1, Tgf-beta2, Tgf-beta3 and Msx2 expression is elevated during frontonasal suture morphogenesis and during active postnatal facial growth. Orthod Craniofac Res 5:227-37

Opperman, L A; Adab, K; Gakunga, P T (2000) Transforming growth factor-beta 2 and TGF-beta 3 regulate fetal rat cranial suture morphogenesis by regulating rates of cell proliferation and apoptosis. Dev Dyn 219:237-47

Opperman, L A (2000) Cranial sutures as intramembranous bone growth sites. Dev Dyn 219:472-85

Opperman, L A; Chhabra, A; Cho, R W et al. (1999) Cranial suture obliteration is induced by removal of transforming growth factor (TGF)-beta 3 activity and prevented by removal of TGF-beta 2 activity from fetal rat calvaria in vitro. J Craniofac Genet Dev Biol 19:164-73

Opperman, L A; Chhabra, A; Nolen, A A et al. (1998) Dura mater maintains rat cranial sutures in vitro by regulating suture cell proliferation and collagen production. J Craniofac Genet Dev Biol 18:150-8