Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
5R29DK040223-02
Application #
3463442
Study Section
General Medicine A Subcommittee 2 (GMA)
Project Start
1989-08-01
Project End
1994-07-31
Budget Start
1990-08-01
Budget End
1991-07-31
Support Year
2
Fiscal Year
1990
Total Cost
Indirect Cost
Name
University of Chicago
Department
Type
Schools of Medicine
DUNS #
225410919
City
Chicago
State
IL
Country
United States
Zip Code
60637
Chen, A; Davis, B H (2000) The DNA binding protein BTEB mediates acetaldehyde-induced, jun N-terminal kinase-dependent alphaI(I) collagen gene expression in rat hepatic stellate cells. Mol Cell Biol 20:2818-26
Chen, A; Davis, B H (1999) UV irradiation activates JNK and increases alphaI(I) collagen gene expression in rat hepatic stellate cells. J Biol Chem 274:158-64
Weiner, J A; Chen, A; Davis, B H (1998) E-box-binding repressor is down-regulated in hepatic stellate cells during up-regulation of mannose 6-phosphate/insulin-like growth factor-II receptor expression in early hepatic fibrogenesis. J Biol Chem 273:15913-9
Davis, B H; Chen, A; Beno, D W (1996) Raf and mitogen-activated protein kinase regulate stellate cell collagen gene expression. J Biol Chem 271:11039-42
Brady, L M; Beno, D W; Davis, B H (1996) Bile acid stimulation of early growth response gene and mitogen-activated protein kinase is protein kinase C-dependent. Biochem J 316 ( Pt 3):765-9
Chen, A; Beno, D W; Davis, B H (1996) Suppression of stellate cell type I collagen gene expression involves AP-2 transmodulation of nuclear factor-1-dependent gene transcription. J Biol Chem 271:25994-8
Beno, D W; Brady, L M; Bissonnette, M et al. (1995) Protein kinase C and mitogen-activated protein kinase are required for 1,25-dihydroxyvitamin D3-stimulated Egr induction. J Biol Chem 270:3642-7
Beno, D W; Mullen, J; Davis, B H (1995) Lipoxygenase inhibitors block PDGF-induced mitogenesis: a MAPK-independent mechanism that blocks fos and egr. Am J Physiol 268:C604-10
Beno, D W; Rapp, U R; Davis, B H (1994) Prostaglandin E suppression of platelet-derived-growth-factor-induced Ito cell mitogenesis occurs independent of raf perinuclear translocation and nuclear proto-oncogene expression. Biochim Biophys Acta 1222:292-300
Beno, D W; Espinal, R; Edelstein, B M et al. (1993) Administration of prostaglandin E1 analog reduces rat hepatic and Ito cell collagen gene expression and collagen accumulation after bile duct ligation injury. Hepatology 17:707-14

Showing the most recent 10 out of 16 publications