Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
5R29DK040527-04
Application #
3463574
Study Section
General Medicine B Study Section (GMB)
Project Start
1988-08-01
Project End
1993-07-31
Budget Start
1991-08-01
Budget End
1992-07-31
Support Year
4
Fiscal Year
1991
Total Cost
Indirect Cost
Name
Vanderbilt University Medical Center
Department
Type
Schools of Medicine
DUNS #
004413456
City
Nashville
State
TN
Country
United States
Zip Code
37212
Ichikawa, I; Kiyama, S; Yoshioka, T (1994) Renal antioxidant enzymes: their regulation and function. Kidney Int 45:1-9
Yoshioka, T; Kawamura, T; Meyrick, B O et al. (1994) Induction of manganese superoxide dismutase by glucocorticoids in glomerular cells. Kidney Int 45:211-9
Kakinuma, Y; Kawamura, T; Bills, T et al. (1992) Blood pressure-independent effect of angiotensin inhibition on vascular lesions of chronic renal failure. Kidney Int 42:46-55
Yoshioka, T; Fogo, A; Beckman, J K (1992) Reduced activity of antioxidant enzymes underlies contrast media-induced renal injury in volume depletion. Kidney Int 41:1008-15
Kawamura, T; Yoshioka, T; Bills, T et al. (1991) Glucocorticoid activates glomerular antioxidant enzymes and protects glomeruli from oxidant injuries. Kidney Int 40:291-301
Beckman, J K; Yoshioka, T; Knobel, S M et al. (1991) Biphasic changes in phospholipid hydroperoxide levels during renal ischemia/reperfusion. Free Radic Biol Med 11:335-40
Yoshioka, T; Ichikawa, I; Fogo, A (1991) Reactive oxygen metabolites cause massive, reversible proteinuria and glomerular sieving defect without apparent ultrastructural abnormality. J Am Soc Nephrol 2:902-12
Yoshioka, T; Bills, T; Moore-Jarrett, T et al. (1990) Role of intrinsic antioxidant enzymes in renal oxidant injury. Kidney Int 38:282-8
Ichikawa, I; Yoshioka, T; Fogo, A et al. (1990) Role of angiotensin II in altered glomerular hemodynamics in congestive heart failure. Kidney Int Suppl 30:S123-6
Yoshioka, T; Ichikawa, I (1989) Glomerular dysfunction induced by polymorphonuclear leukocyte-derived reactive oxygen species. Am J Physiol 257:F53-9

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