21-Hydroxylase Deficiency - Mutations and Mechanisms

Donohoue, Patricia A.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
• Type: First Independent Research Support & Transition (FIRST) Awards (R29)
• Project #: 7R29DK041260-03
• Application #: 3463768
• Study Section: Endocrinology Study Section (END)
• Project Start: 1989-07-01
• Project End: 1994-06-30
• Budget Start: 1990-07-15
• Budget End: 1991-06-30
• Support Year: 3
• Fiscal Year: 1990

Institution

• Name: University of Iowa
• Type: Schools of Medicine
• DUNS #: 041294109
• City: Iowa City
• State: IA
• Country: United States
• Zip Code: 52242

Publications

Donohoue, P A; Collins, M M (1992) The human complement C4B/steroid 21-hydroxylase (CYP21) and complement C4A/21-hydroxylase pseudogene (CYP21P) intergenic sequences: comparison and identification of possible regulatory elements. Biochem Biophys Res Commun 186:256-62

Migeon, C J; Donohoue, P A (1991) Congenital adrenal hyperplasia caused by 21-hydroxylase deficiency. Its molecular basis and its remaining therapeutic problems. Endocrinol Metab Clin North Am 20:277-96

Donohoue, P A; Sandrini Neto, R; Collins, M M et al. (1990) Exon 7 Ncol restriction site within CYP21B (steroid 21-hydroxylase) is a normal polymorphism. Mol Endocrinol 4:1354-62