Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
5R29DK044617-06
Application #
2016479
Study Section
General Medicine A Subcommittee 2 (GMA)
Project Start
1992-09-30
Project End
1997-09-29
Budget Start
1996-09-30
Budget End
1997-09-29
Support Year
6
Fiscal Year
1996
Total Cost
Indirect Cost
Name
State University of NY, Binghamton
Department
Biology
Type
Schools of Arts and Sciences
DUNS #
090189965
City
Binghamton
State
NY
Country
United States
Zip Code
13902
Goodrich, M E; McGee, D W (1999) Effect of intestinal epithelial cell cytokines on mucosal B-cell IgA secretion: enhancing effect of epithelial-derived IL-6 but not TGF-beta on IgA+ B cells. Immunol Lett 67:11-4
Goodrich, M E; McGee, D W (1999) Preferential enhancement of B cell IgA secretion by intestinal epithelial cell-derived cytokines and interleukin-2. Immunol Invest 28:67-75
Vitkus, S J; Hanifin, S A; McGee, D W (1998) Factors affecting Caco-2 intestinal epithelial cell interleukin-6 secretion. In Vitro Cell Dev Biol Anim 34:660-4
Jiang, Y; McGee, D W (1998) Regulation of human lymphocyte IL-4 secretion by intestinal epithelial cell-derived interleukin-7 and transforming growth factor-beta. Clin Immunol Immunopathol 88:287-96
Goodrich, M E; McGee, D W (1998) Regulation of mucosal B cell immunoglobulin secretion by intestinal epithelial cell-derived cytokines. Cytokine 10:948-55
McGee, D W; Vitkus, S J (1996) IL-4 enhances IEC-6 intestinal epithelial cell proliferation yet has no effect on IL-6 secretion. Clin Exp Immunol 105:274-7
Mascarenhas, J O; Goodrich, M E; Eichelberger, H et al. (1996) Polarized secretion of IL-6 by IEC-6 intestinal epithelial cells: differential effects of IL-1 beta and TNF-alpha. Immunol Invest 25:333-40
McGee, D W; Vitkus, S J; Lee, P (1996) The effect of cytokine stimulation on IL-1 receptor mRNA expression by intestinal epithelial cells. Cell Immunol 168:276-80
McGee, D W; Bamberg, T; Vitkus, S J et al. (1995) A synergistic relationship between TNF-alpha, IL-1 beta, and TGF-beta 1 on IL-6 secretion by the IEC-6 intestinal epithelial cell line. Immunology 86:6-11
McGee, D W; Elson, C O; McGhee, J R (1993) Enhancing effect of cholera toxin on interleukin-6 secretion by IEC-6 intestinal epithelial cells: mode of action and augmenting effect of inflammatory cytokines. Infect Immun 61:4637-44