Project Start
1993-08-01
Project End
1998-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Minnesota Twin Cities
Department
Pharmacology
Type
Schools of Medicine
DUNS #
168559177
City
Minneapolis
State
MN
Country
United States
Zip Code
55455
Wei, L N; Chang, L; HU, X (1999) Studies of the type I cellular retinoic acid-binding protein mutants and their biological activities. Mol Cell Biochem 200:69-76
Yu, Z; Lee, C H; Chinpaisal, C et al. (1998) A constitutive nuclear localization signal from the second zinc-finger of orphan nuclear receptor TR2. J Endocrinol 159:53-60
Lee, C H; Chinpaisal, C; Wei, L N (1998) A novel nuclear receptor heterodimerization pathway mediated by orphan receptors TR2 and TR4. J Biol Chem 273:25209-15
Chinpaisal, C; Lee, C H; Wei, L N (1998) Mechanisms of the mouse orphan nuclear receptor TR2-11-mediated gene suppression. J Biol Chem 273:18077-85
Lee, C H; Chinpaisal, C; Wei, L N (1998) Cloning and characterization of mouse RIP140, a corepressor for nuclear orphan receptor TR2. Mol Cell Biol 18:6745-55
Chinpaisal, C; Chang, L; Hu, X et al. (1997) The orphan nuclear receptor TR2 suppresses a DR4 hormone response element of the mouse CRABP-I gene promoter. Biochemistry 36:14088-95
Chang, L; Wei, L N (1997) Characterization of a negative response DNA element in the upstream region of the cellular retinoic acid-binding protein-I gene of the mouse. J Biol Chem 272:10144-50
Wei, L N (1997) Transgenic animals as new approaches in pharmacological studies. Annu Rev Pharmacol Toxicol 37:119-41
Lee, C H; Chang, L; Wei, L N (1997) Distinct expression patterns and biological activities of two isoforms of the mouse orphan receptor TR2. J Endocrinol 152:245-55
Wei, L N; Lee, C H; Filipcik, P et al. (1997) Regulation of the mouse cellular retinoic acid-binding protein-I gene by thyroid hormone and retinoids in transgenic mouse embryos and P19 cells. J Endocrinol 155:35-46

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