Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
5R29DK047333-02
Application #
2146844
Study Section
General Medicine B Study Section (GMB)
Project Start
1995-07-10
Project End
2000-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
Duke University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
071723621
City
Durham
State
NC
Country
United States
Zip Code
27705

  Publications

Flannery, Patrick J; Spurney, Robert F (2002) Desensitization of the mouse thromboxane A2 receptor (TP) by G protein-coupled receptor kinases (Grks). Prostaglandins Other Lipid Mediat 70:79-90
Spurney, R F (2001) Regulation of thromboxane receptor (TP) phosphorylation by protein phosphatase 1 (PP1) and PP2A. J Pharmacol Exp Ther 296:592-9
Spurney, R F; Pi, M; Flannery, P et al. (1999) Aluminum is a weak agonist for the calcium-sensing receptor. Kidney Int 55:1750-8
Spurney, R F (1998) Effect of receptor number on desensitization of the mouse thromboxane receptor. Biochem Pharmacol 55:1271-81
Spurney, R F (1998) Role of C-terminal serines in desensitization and phosphorylation of the mouse thromboxane receptor. J Biol Chem 273:28496-503
Coffman, T M; Spurney, R F; Mannon, R B et al. (1998) Thromboxane A2 modulates the fibrinolytic system in glomerular mesangial cells. Am J Physiol 275:F262-9
Spurney, R F; Coffman, T M (1997) The C-terminus of the thromboxane receptor contributes to coupling and desensitization in a mouse mesangial cell line. J Pharmacol Exp Ther 283:207-15