Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
5R29DK048820-02
Application #
2149294
Study Section
General Medicine A Subcommittee 2 (GMA)
Project Start
1995-01-01
Project End
1999-11-30
Budget Start
1995-12-01
Budget End
1996-11-30
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Yale University
Department
Surgery
Type
Schools of Medicine
DUNS #
082359691
City
New Haven
State
CT
Country
United States
Zip Code
06520
Lauffer, J M; Tang, L H; Zhang, T et al. (2001) PACAP mediates the neural proliferative pathway of Mastomys enterochromaffin-like cell transformation. Regul Pept 102:157-64
Kidd, M; Tang, L H; Modlin, I M et al. (2000) Gastrin-mediated alterations in gastric epithelial apoptosis and proliferation in a mastomys rodent model of gastric neoplasia. Digestion 62:143-51
Lauffer, J M; Modlin, I M; Hinoue, T et al. (1999) Pituitary adenylate cyclase-activating polypeptide modulates gastric enterochromaffin-like cell proliferation in rats. Gastroenterology 116:623-35
Luque, E A; Tang, L H; Bortecen, K H et al. (1998) Gastrin-regulated expression of p53 in transformed enterochromaffin-like cells in the African rodent mastomys. J Clin Gastroenterol 27 Suppl 1:S116-24
Schmid, S W; Modlin, I M; Tang, L H et al. (1998) Telenzepine-sensitive muscarinic receptors on rat pancreatic acinar cells. Am J Physiol 274:G734-41
Kidd, M; Tang, L H; Schmid, S W et al. (1998) A polyamine pathway-mediated mitogenic mechanism in enterochromaffin-like cells of Mastomys. Am J Physiol 275:G370-6
Tang, L H; Luque, E A; Efstathiou, J A et al. (1997) Gastrin receptor expression and function during rapid transformation of the enterochromaffin-like cells in an African rodent. Regul Pept 72:9-18
Tang, L H; Modlin, I M; Lawton, G P et al. (1996) The role of transforming growth factor alpha in the enterochromaffin-like cell tumor autonomy in an African rodent mastomys. Gastroenterology 111:1212-23
Borin, J F; Tang, L H; Kidd, M et al. (1996) Somatostatin receptor regulation of gastric enterochromaffin-like cell transformation to gastric carcinoid. Surgery 120:1026-32