Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
5R29DK050189-02
Application #
2017036
Study Section
General Medicine A Subcommittee 2 (GMA)
Project Start
1995-09-25
Project End
2000-08-31
Budget Start
1996-09-11
Budget End
1997-08-31
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Brigham and Women's Hospital
Department
Type
DUNS #
071723621
City
Boston
State
MA
Country
United States
Zip Code
02115
Onyiah, Joseph C; Schaefer, Rachel E M; Colgan, Sean P (2018) A Central Role for Heme Oxygenase-1 in the Control of Intestinal Epithelial Chemokine Expression. J Innate Immun 10:228-238
Curtis, Valerie F; Cartwright, Ian M; Lee, J Scott et al. (2018) Neutrophils as sources of dinucleotide polyphosphates and metabolism by epithelial ENPP1 to influence barrier function via adenosine signaling. Mol Biol Cell 29:2687-2699
Kuhn, K A; Schulz, H M; Regner, E H et al. (2018) Bacteroidales recruit IL-6-producing intraepithelial lymphocytes in the colon to promote barrier integrity. Mucosal Immunol 11:357-368
Glover, Louise E; Colgan, Sean P (2017) Epithelial Barrier Regulation by Hypoxia-Inducible Factor. Ann Am Thorac Soc 14:S233-S236
Kao, Daniel J; Saeedi, Bejan J; Kitzenberg, David et al. (2017) Intestinal Epithelial Ecto-5'-Nucleotidase (CD73) Regulates Intestinal Colonization and Infection by Nontyphoidal Salmonella. Infect Immun 85:
Lanis, Jordi M; Kao, Daniel J; Alexeev, Erica E et al. (2017) Tissue metabolism and the inflammatory bowel diseases. J Mol Med (Berl) 95:905-913
Wang, Ruth X; Colgan, Sean P (2017) Special pro-resolving mediator (SPM) actions in regulating gastro-intestinal inflammation and gut mucosal immune responses. Mol Aspects Med 58:93-101
Zheng, Leon; Kelly, Caleb J; Battista, Kayla D et al. (2017) Microbial-Derived Butyrate Promotes Epithelial Barrier Function through IL-10 Receptor-Dependent Repression of Claudin-2. J Immunol 199:2976-2984
Hall, Caroline H T; Campbell, Eric L; Colgan, Sean P (2017) Neutrophils as Components of Mucosal Homeostasis. Cell Mol Gastroenterol Hepatol 4:329-337
Ehrentraut, Stefan F; Curtis, Valerie F; Wang, Ruth X et al. (2016) Perturbation of neddylation-dependent NF-?B responses in the intestinal epithelium drives apoptosis and inhibits resolution of mucosal inflammation. Mol Biol Cell :

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