Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
1R29DK050190-01A1
Application #
2151220
Study Section
General Medicine B Study Section (GMB)
Project Start
1996-06-10
Project End
2001-05-31
Budget Start
1996-06-10
Budget End
1997-05-31
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Texas Health Science Center San Antonio
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
800772162
City
San Antonio
State
TX
Country
United States
Zip Code
78229
Lee, Hak Joo; Lee, Doug Yoon; Mariappan, Meenalakshmi M et al. (2017) Hydrogen sulfide inhibits high glucose-induced NADPH oxidase 4 expression and matrix increase by recruiting inducible nitric oxide synthase in kidney proximal tubular epithelial cells. J Biol Chem 292:5665-5675
Lee, Hak Joo; Feliers, Denis; Mariappan, Meenalakshmi M et al. (2015) Tadalafil Integrates Nitric Oxide-Hydrogen Sulfide Signaling to Inhibit High Glucose-induced Matrix Protein Synthesis in Podocytes. J Biol Chem 290:12014-26
Mariappan, Meenalakshmi M; Prasad, Sanjay; D'Silva, Kristin et al. (2014) Activation of glycogen synthase kinase 3? ameliorates diabetes-induced kidney injury. J Biol Chem 289:35363-75
Lee, Hak Joo; Mariappan, Meenalakshmi M; Feliers, Denis et al. (2012) Hydrogen sulfide inhibits high glucose-induced matrix protein synthesis by activating AMP-activated protein kinase in renal epithelial cells. J Biol Chem 287:4451-61
Sataranatarajan, Kavithalakshmi; Feliers, Denis; Mariappan, Meenalakshmi M et al. (2012) Molecular events in matrix protein metabolism in the aging kidney. Aging Cell 11:1065-73
Mariappan, Meenalakshmi M; D'Silva, Kristin; Lee, Myung Ja et al. (2011) Ribosomal biogenesis induction by high glucose requires activation of upstream binding factor in kidney glomerular epithelial cells. Am J Physiol Renal Physiol 300:F219-30
Lee, Hsiang-Ying; Johnson, Kirby D; Boyer, Meghan E et al. (2011) Relocalizing genetic loci into specific subnuclear neighborhoods. J Biol Chem 286:18834-44
Lee, Myung-Ja; Feliers, Denis; Sataranatarajan, Kavithalakshmi et al. (2010) Resveratrol ameliorates high glucose-induced protein synthesis in glomerular epithelial cells. Cell Signal 22:65-70
Block, Karen; Gorin, Yves; New, David D et al. (2010) The NADPH oxidase subunit p22phox inhibits the function of the tumor suppressor protein tuberin. Am J Pathol 176:2447-55
Kasinath, Balakuntalam S; Feliers, Denis; Sataranatarajan, Kavithalakshmi et al. (2009) Regulation of mRNA translation in renal physiology and disease. Am J Physiol Renal Physiol 297:F1153-65

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