Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
7R29EY008061-02
Application #
3465724
Study Section
Visual Sciences A Study Section (VISA)
Project Start
1990-02-01
Project End
1994-07-31
Budget Start
1990-02-01
Budget End
1990-07-31
Support Year
2
Fiscal Year
1989
Total Cost
Indirect Cost
Name
Good Samaritan Hosp & Medical Center(Prtlnd,OR)
Department
Type
DUNS #
City
Portland
State
OR
Country
United States
Zip Code
97210
Jastrzebska, Beata; Chen, Yuanyuan; Orban, Tivadar et al. (2015) Disruption of Rhodopsin Dimerization with Synthetic Peptides Targeting an Interaction Interface. J Biol Chem 290:25728-44
Chen, Yuanyuan; Jastrzebska, Beata; Cao, Pengxiu et al. (2014) Inherent instability of the retinitis pigmentosa P23H mutant opsin. J Biol Chem 289:9288-303
Mustafi, Debarshi; Kikano, Sandra; Palczewski, Krzysztof (2014) Serial block face-scanning electron microscopy: a method to study retinal degenerative phenotypes. Curr Protoc Mouse Biol 4:197-204
Tu, Xiongying; Palczewski, Krzysztof (2014) The macular degeneration-linked C1QTNF5 (S163) mutation causes higher-order structural rearrangements. J Struct Biol 186:86-94
Orban, Tivadar; Jastrzebska, Beata; Palczewski, Krzysztof (2014) Structural approaches to understanding retinal proteins needed for vision. Curr Opin Cell Biol 27:32-43
Chen, Yuanyuan; Tang, Hong; Seibel, William et al. (2014) Identification and characterization of novel inhibitors of Mammalian aspartyl aminopeptidase. Mol Pharmacol 86:231-42
Jastrzebska, Beata; Ringler, Philippe; Palczewski, Krzysztof et al. (2013) The rhodopsin-transducin complex houses two distinct rhodopsin molecules. J Struct Biol 182:164-72
Kevany, Brian M; Tsybovsky, Yaroslav; Campuzano, Iain D G et al. (2013) Structural and functional analysis of the native peripherin-ROM1 complex isolated from photoreceptor cells. J Biol Chem 288:36272-84
Vahedi-Faridi, Ardeschir; Jastrzebska, Beata; Palczewski, Krzysztof et al. (2013) 3D imaging and quantitative analysis of small solubilized membrane proteins and their complexes by transmission electron microscopy. Microscopy (Oxf) 62:95-107
Palczewski, Krzysztof; Kiser, Philip D (2013) Biochemistry. As good as chocolate. Science 340:562-3

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