Intermediates Involved in DNA Cleavage

Greenberg, Marc M.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of General Medical Sciences (NIGMS)
• Type: First Independent Research Support & Transition (FIRST) Awards (R29)
• Project #: 5R29GM046534-05
• Application #: 2184036
• Study Section: Bio-Organic and Natural Products Chemistry Study Section (BNP)
• Project Start: 1992-07-01
• Project End: 1997-08-31
• Budget Start: 1996-07-01
• Budget End: 1997-08-31
• Support Year: 5
• Fiscal Year: 1996

Institution

• Name: Colorado State University-Fort Collins
• Department: Chemistry
• Type: Schools of Arts and Sciences
• DUNS #: 112617480
• City: Fort Collins
• State: CO
• Country: United States
• Zip Code: 80523

Publications

Tronche, C; Goodman, B K; Greenberg, M M (1998) DNA damage induced via independent generation of the radical resulting from formal hydrogen atom abstraction from the C1'-position of a nucleotide. Chem Biol 5:263-71

Greenberg, M M; Matray, T J (1997) Inhibition of klenow fragment (exo-) catalyzed DNA polymerization by (5R)-5,6-dihydro-5-hydroxythymidine and structural analogue 5,6-dihydro-5-methylthymidine. Biochemistry 36:14071-9

Matray, T J; Haxton, K J; Greenberg, M M (1995) The effects of the ring fragmentation product of thymidine C5-hydrate on phosphodiesterases and klenow (exo-) fragment. Nucleic Acids Res 23:4642-8