Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
5R29GM047127-05
Application #
2184544
Study Section
Surgery, Anesthesiology and Trauma Study Section (SAT)
Project Start
1992-02-01
Project End
1997-01-31
Budget Start
1996-02-01
Budget End
1997-01-31
Support Year
5
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Boston Medical Center
Department
Type
DUNS #
005492160
City
Boston
State
MA
Country
United States
Zip Code
02118
Lo, S K; Golenbock, D T; Sass, P M et al. (1997) Engagement of the Lewis X antigen (CD15) results in monocyte activation. Blood 89:307-14
Lodie, T A; Savedra Jr, R; Golenbock, D T et al. (1997) Stimulation of macrophages by lipopolysaccharide alters the phosphorylation state, conformation, and function of PU.1 via activation of casein kinase II. J Immunol 158:1848-56
Levitz, S M; Tabuni, A; Nong, S H et al. (1996) Effects of interleukin-10 on human peripheral blood mononuclear cell responses to Cryptococcus neoformans, Candida albicans, and lipopolysaccharide. Infect Immun 64:945-51
Savedra Jr, R; Delude, R L; Ingalls, R R et al. (1996) Mycobacterial lipoarabinomannan recognition requires a receptor that shares components of the endotoxin signaling system. J Immunol 157:2549-54
Ingalls, R R; Rice, P A; Qureshi, N et al. (1995) The inflammatory cytokine response to Chlamydia trachomatis infection is endotoxin mediated. Infect Immun 63:3125-30
Wensing, G; Sabra, R; Branch, R A (1995) Relationship between oxidative hepatic metabolism, urinary sodium excretion and sympathetic nerve activity in experimental cirrhosis in the rat. Z Gastroenterol 33:1-4
Ingalls, R R; Golenbock, D T (1995) CD11c/CD18, a transmembrane signaling receptor for lipopolysaccharide. J Exp Med 181:1473-9
Golenbock, D T; Bach, R R; Lichenstein, H et al. (1995) Soluble CD14 promotes LPS activation of CD14-deficient PNH monocytes and endothelial cells. J Lab Clin Med 125:662-71
Delude, R L; Savedra Jr, R; Zhao, H et al. (1995) CD14 enhances cellular responses to endotoxin without imparting ligand-specific recognition. Proc Natl Acad Sci U S A 92:9288-92
Fagan, M A; Liu, Y; Stutz, P et al. (1994) Acyclic analogue of lipid A stimulates TNF-alpha and arachidonate release via a unique LPS-signaling pathway. J Immunol 153:5230-8

Showing the most recent 10 out of 14 publications