Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
5R29GM049076-03
Application #
2186611
Study Section
Bio-Organic and Natural Products Chemistry Study Section (BNP)
Project Start
1994-04-01
Project End
1999-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
University of California Irvine
Department
Chemistry
Type
Schools of Arts and Sciences
DUNS #
161202122
City
Irvine
State
CA
Country
United States
Zip Code
92697

  Publications

Zheng, Jing; Liu, Cong; Sawaya, Michael R et al. (2011) Macrocyclic ýý-sheet peptides that inhibit the aggregation of a tau-protein-derived hexapeptide. J Am Chem Soc 133:3144-57
Liu, Cong; Sawaya, Michael R; Cheng, Pin-Nan et al. (2011) Characteristics of amyloid-related oligomers revealed by crystal structures of macrocyclic ?-sheet mimics. J Am Chem Soc 133:6736-44
Khakshoor, Omid; Lin, Aaron J; Korman, Tyler P et al. (2010) X-ray crystallographic structure of an artificial beta-sheet dimer. J Am Chem Soc 132:11622-8
Levin, Sergiy; Nowick, James S (2009) A new artificial beta-sheet that dimerizes through parallel beta-sheet interactions. Org Lett 11:1003-6
Khakshoor, Omid; Nowick, James S (2009) Use of disulfide ""staples"" to stabilize beta-sheet quaternary structure. Org Lett 11:3000-3