Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
5R29GM052071-02
Application #
2190957
Study Section
Biophysical Chemistry Study Section (BBCB)
Project Start
1995-01-01
Project End
1999-12-31
Budget Start
1996-01-01
Budget End
1996-12-31
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Maryland Baltimore
Department
Biochemistry
Type
Schools of Medicine
DUNS #
003255213
City
Baltimore
State
MD
Country
United States
Zip Code
21201
Garbuglia, M; Verzini, M; Rustandi, R R et al. (1999) Role of the C-terminal extension in the interaction of S100A1 with GFAP, tubulin, the S100A1- and S100B-inhibitory peptide, TRTK-12, and a peptide derived from p53, and the S100A1 inhibitory effect on GFAP polymerization. Biochem Biophys Res Commun 254:36-41
Landar, A; Rustandi, R R; Weber, D J et al. (1998) S100A1 utilizes different mechanisms for interacting with calcium-dependent and calcium-independent target proteins. Biochemistry 37:17429-38
Wilder, P T; Rustandi, R R; Drohat, A C et al. (1998) S100B(betabeta) inhibits the protein kinase C-dependent phosphorylation of a peptide derived from p53 in a Ca2+-dependent manner. Protein Sci 7:794-8
Rustandi, R R; Drohat, A C; Baldisseri, D M et al. (1998) The Ca(2+)-dependent interaction of S100B(beta beta) with a peptide derived from p53. Biochemistry 37:1951-60
Tenenholz, T C; Rogowski, R S; Collins, J H et al. (1997) Solution structure for Pandinus toxin K-alpha (PiTX-K alpha), a selective blocker of A-type potassium channels. Biochemistry 36:2763-71
Landar, A; Hall, T L; Cornwall, E H et al. (1997) The role of cysteine residues in S100B dimerization and regulation of target protein activity. Biochim Biophys Acta 1343:117-29
Chaudhuri, D; Horrocks Jr, W D; Amburgey, J C et al. (1997) Characterization of lanthanide ion binding to the EF-hand protein S100 beta by luminescence spectroscopy. Biochemistry 36:9674-80
Drohat, A C; Nenortas, E; Beckett, D et al. (1997) Oligomerization state of S100B at nanomolar concentration determined by large-zone analytical gel filtration chromatography. Protein Sci 6:1577-82
Drohat, A C; Amburgey, J C; Abildgaard, F et al. (1996) Solution structure of rat apo-S100B(beta beta) as determined by NMR spectroscopy. Biochemistry 35:11577-88
Rogowski, R S; Collins, J H; O'Neill, T J et al. (1996) Three new toxins from the scorpion Pandinus imperator selectively block certain voltage-gated K+ channels. Mol Pharmacol 50:1167-77

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