Funding Agency

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
5R29HD029924-02
Application #
2202286
Study Section
Reproductive Endocrinology Study Section (REN)
Project Start
1995-09-01
Project End
2000-05-31
Budget Start
1996-09-01
Budget End
1997-08-31
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
Case Western Reserve University
Department
Obstetrics & Gynecology
Type
Schools of Medicine
DUNS #
077758407
City
Cleveland
State
OH
Country
United States
Zip Code
44106

  Publications

Gorodeski, George I (2007) Estrogen decrease in tight junctional resistance involves matrix-metalloproteinase-7-mediated remodeling of occludin. Endocrinology 148:218-31
Gorodeski, George I (2007) Estrogen modulation of epithelial permeability in cervical-vaginal cells of premenopausal and postmenopausal women. Menopause 14:1012-9
Gorodeski, George I (2007) Estrogen modulation of MgATPase activity of nonmuscle myosin-II-B filaments. Endocrinology 148:279-92
Feng, Y H; Li, X; Zeng, R et al. (2006) Endogenously expressed truncated P2X7 receptor lacking the C-terminus is preferentially upregulated in epithelial cancer cells and fails to mediate ligand-induced pore formation and apoptosis. Nucleosides Nucleotides Nucleic Acids 25:1271-6
Li, X; Gorodeski, G I (2006) Apically sorted P2X7 receptors mediate purinergic-induced pore formation preferentially in apical domains of the plasma membrane. Nucleosides Nucleotides Nucleic Acids 25:1045-9
Li, Xin; Zhou, Lingying; Feng, Ying-Hong et al. (2006) The P2X7 receptor: a novel biomarker of uterine epithelial cancers. Cancer Epidemiol Biomarkers Prev 15:1906-13
Li, Xin; Zhou, Lingying; Gorodeski, George I (2006) Estrogen regulates epithelial cell deformability by modulation of cortical actomyosin through phosphorylation of nonmuscle myosin heavy-chain II-B filaments. Endocrinology 147:5236-48
Li, Xin; Gorodeski, George (2006) Non-muscle myosin-II-B filament regulation of paracellular resistance in cervical epithelial cells is associated with modulation of the cortical acto-myosin. J Soc Gynecol Investig 13:579-91
Zhu, Ling; Li, Xin; Zeng, Robin et al. (2006) Changes in tight junctional resistance of the cervical epithelium are associated with modulation of content and phosphorylation of occludin 65-kilodalton and 50-kilodalton forms. Endocrinology 147:977-89
Gorodeski, George I (2005) Aging and estrogen effects on transcervical-transvaginal epithelial permeability. J Clin Endocrinol Metab 90:345-51

Showing the most recent 10 out of 40 publications