Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
5R29HL038206-02
Application #
3470991
Study Section
Experimental Cardiovascular Sciences Study Section (ECS)
Project Start
1987-04-01
Project End
1988-06-30
Budget Start
1988-04-01
Budget End
1988-06-30
Support Year
2
Fiscal Year
1988
Total Cost
Indirect Cost
Name
Brigham and Women's Hospital
Department
Type
DUNS #
071723621
City
Boston
State
MA
Country
United States
Zip Code
02115
Fujii, Masakazu; Amanso, Angélica; Abrahão, Thalita B et al. (2016) Polymerase delta-interacting protein 2 regulates collagen accumulation via activation of the Akt/mTOR pathway in vascular smooth muscle cells. J Mol Cell Cardiol 92:21-9
Brown, David I; Griendling, Kathy K (2015) Regulation of signal transduction by reactive oxygen species in the cardiovascular system. Circ Res 116:531-49
Abrahao, Thalita B; Griendling, Kathy K (2015) Nuclear factor (erythroid-derived 2)-like 2, the brake in oxidative stress that nicotinamide adenine dinucleotide phosphate-oxidase-4 needs to protect the heart. Hypertension 65:499-501
Datla, Srinivasa Raju; McGrail, Daniel J; Vukelic, Sasa et al. (2014) Poldip2 controls vascular smooth muscle cell migration by regulating focal adhesion turnover and force polarization. Am J Physiol Heart Circ Physiol 307:H945-57
Brown, David I; Lassègue, Bernard; Lee, Minyoung et al. (2014) Poldip2 knockout results in perinatal lethality, reduced cellular growth and increased autophagy of mouse embryonic fibroblasts. PLoS One 9:e96657
Vukelic, Sasa; Griendling, Kathy K (2014) Angiotensin II, from vasoconstrictor to growth factor: a paradigm shift. Circ Res 114:754-7
Amanso, Angélica M; Lassègue, Bernard; Joseph, Giji et al. (2014) Polymerase ?-interacting protein 2 promotes postischemic neovascularization of the mouse hindlimb. Arterioscler Thromb Vasc Biol 34:1548-55
Sutliff, Roy L; Hilenski, Lula L; Amanso, Angélica M et al. (2013) Polymerase delta interacting protein 2 sustains vascular structure and function. Arterioscler Thromb Vasc Biol 33:2154-61
Martin-Garrido, Abel; Williams, Holly C; Lee, Minyoung et al. (2013) Transforming growth factor ? inhibits platelet derived growth factor-induced vascular smooth muscle cell proliferation via Akt-independent, Smad-mediated cyclin D1 downregulation. PLoS One 8:e79657
Williams, Holly C; San Martín, Alejandra; Adamo, Candace M et al. (2012) Role of coronin 1B in PDGF-induced migration of vascular smooth muscle cells. Circ Res 111:56-65

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