Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
1R29HL040395-01
Application #
3471931
Study Section
Cardiovascular Study Section (CVA)
Project Start
1988-04-01
Project End
1993-03-31
Budget Start
1988-04-01
Budget End
1989-03-31
Support Year
1
Fiscal Year
1988
Total Cost
Indirect Cost
Name
Wake Forest University Health Sciences
Department
Type
Schools of Medicine
DUNS #
041418799
City
Winston-Salem
State
NC
Country
United States
Zip Code
27106
Johnston, W E; Vinten-Johansen, J; Shugart, H E et al. (1993) Collateral perfusion through overlapping vessels reduces canine right ventricular ischemic injury from positive end-expiratory pressure. Crit Care Med 21:721-32
Toombs, C F; McGee, D S; Johnston, W E et al. (1993) Protection from ischaemic-reperfusion injury with adenosine pretreatment is reversed by inhibition of ATP sensitive potassium channels. Cardiovasc Res 27:623-9
Johnston, W E; Vinten-Johansen, J; Shugart, H E et al. (1992) Positive end-expiratory pressure potentiates the severity of canine right ventricular ischemia-reperfusion injury. Am J Physiol 262:H168-76
Applegate, R J; Johnston, W E; Vinten-Johansen, J et al. (1992) Restraining effect of intact pericardium during acute volume loading. Am J Physiol 262:H1725-33
Nakanishi, K; Vinten-Johansen, J; Lefer, D J et al. (1992) Intracoronary L-arginine during reperfusion improves endothelial function and reduces infarct size. Am J Physiol 263:H1650-8
Nakamoto, T; Li, K S; Johnston, W E et al. (1992) Differential effects of positive end expiratory pressure and cardiac tamponade on left-right ventricular mechanical function in the dog. Cardiovasc Res 26:148-52
Toombs, C F; McGee, S; Johnston, W E et al. (1992) Myocardial protective effects of adenosine. Infarct size reduction with pretreatment and continued receptor stimulation during ischemia. Circulation 86:986-94
Vinten-Johansen, J; Julian, J S; Yokoyama, H et al. (1991) Efficacy of myocardial protection with hypothermic blood cardioplegia depends on oxygen. Ann Thorac Surg 52:939-48
Vinten-Johansen, J; Gayheart, P A; Johnston, W E et al. (1991) Regional function, blood flow, and oxygen utilization relations in repetitively occluded-reperfused canine myocardium. Am J Physiol 261:H538-47
Toombs, C F; Vinten-Johansen, J; Yokoyama, H et al. (1991) Nonlinearity of indexes of left ventricular performance: effects on estimation of slope and diameter axis intercepts. Am J Physiol 260:H1802-9

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