Zinc Cardioprotection - Role of Cellular Copper and Iron

Powell, Saul R.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Heart, Lung, and Blood Institute (NHLBI)
• Type: First Independent Research Support & Transition (FIRST) Awards (R29)
• Project #: 5R29HL045534-04
• Application #: 2222217
• Study Section: Cardiovascular and Renal Study Section (CVB)
• Project Start: 1993-02-01
• Project End: 1998-01-31
• Budget Start: 1996-02-01
• Budget End: 1998-01-31
• Support Year: 4
• Fiscal Year: 1996

Institution

• Name: North Shore University Hospital
• City: Manhasset
• State: NY
• Country: United States
• Zip Code: 11030

Publications

Powell, S R; Gurzenda, E M; Wingertzahn, M A et al. (1999) Promotion of copper excretion from the isolated rat heart attenuates postischemic cardiac oxidative injury. Am J Physiol 277:H956-62

Powell, S R; Hall, D; Aiuto, L et al. (1994) Zinc improves postischemic recovery of isolated rat hearts through inhibition of oxidative stress. Am J Physiol 266:H2497-507

Powell, S R; Wapnir, R A (1994) Adventitious redox-active metals in Krebs-Henseleit buffer can contribute to Langendorff heart experimental results. J Mol Cell Cardiol 26:769-78

Powell, S R (1994) Salicylate trapping of .OH as a tool for studying post-ischemic oxidative injury in the isolated rat heart. Free Radic Res 21:355-70