Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
5R29HL046716-05
Application #
2223154
Study Section
Surgery, Anesthesiology and Trauma Study Section (SAT)
Project Start
1992-08-01
Project End
1997-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
5
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Beth Israel Deaconess Medical Center
Department
Type
DUNS #
076593722
City
Boston
State
MA
Country
United States
Zip Code
02215
Feng, Jun; Liu, Yuhong; Sabe, Ashraf A et al. (2016) Differential impairment of adherens-junction expression/phosphorylation after cardioplegia in diabetic versus non-diabetic patients. Eur J Cardiothorac Surg 49:937-43
Liu, Yuhong; Xie, An; Singh, Arun K et al. (2015) Inactivation of Endothelial Small/Intermediate Conductance of Calcium-Activated Potassium Channels Contributes to Coronary Arteriolar Dysfunction in Diabetic Patients. J Am Heart Assoc 4:e002062
Potz, Brittany A; Sabe, Ashraf A; Elmadhun, Nassrene Y et al. (2015) Calpain inhibition decreases myocardial apoptosis in a swine model of chronic myocardial ischemia. Surgery 158:445-52
Sabe, Ashraf A; Dalal, Rahul S; Chu, Louis M et al. (2015) Preoperative gene expression may be associated with neurocognitive decline after cardiopulmonary bypass. J Thorac Cardiovasc Surg 149:613-22; discussion 622-3
Feng, Jun; Liu, Yuhong; Dobrilovic, Nikola et al. (2013) Altered apoptosis-related signaling after cardioplegic arrest in patients with uncontrolled type 2 diabetes mellitus. Circulation 128:S144-51
Feng, Jun; Liu, Yuhong; Chu, Louis M et al. (2012) Changes in microvascular reactivity after cardiopulmonary bypass in patients with poorly controlled versus controlled diabetes. Circulation 126:S73-80
Feng, Jun; Liu, Yuhong; Singh, Arun K et al. (2011) Impaired contractile response of human peripheral arterioles to thromboxane A-2 after cardiopulmonary bypass. Surgery 150:263-71
Feng, Jun; Liu, Yuhong; Khabbaz, Kamal R et al. (2011) Decreased contractile response to endothelin-1 of peripheral microvasculature from diabetic patients. Surgery 149:247-52
Feng, Jun; Liu, Yuhong; Chu, Louis M et al. (2011) Thromboxane-induced contractile response of human coronary arterioles is diminished after cardioplegic arrest. Ann Thorac Surg 92:829-36
Feng, Jun; Damrauer, Scott M; Lee, Monica et al. (2010) Endothelium-dependent coronary vasodilatation requires NADPH oxidase-derived reactive oxygen species. Arterioscler Thromb Vasc Biol 30:1703-10

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