Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
5R29HL047598-04
Application #
2223786
Study Section
Experimental Cardiovascular Sciences Study Section (ECS)
Project Start
1992-02-01
Project End
1997-01-31
Budget Start
1995-02-01
Budget End
1997-01-31
Support Year
4
Fiscal Year
1995
Total Cost
Indirect Cost

  Institution

Name
University of Kentucky
Department
Pharmacology
Type
Schools of Medicine
DUNS #
832127323
City
Lexington
State
KY
Country
United States
Zip Code
40506

  Publications

Lipke, D W; Newman, P S; Tofiq, S et al. (1997) Multiple polyamine regulatory pathways control compensatory cardiovascular hypertrophy in coarctation hypertension. Clin Exp Hypertens 19:269-95
Lipke, D W; Newman, P S; Tofiq, S et al. (1997) Eflornithine alters changes in vascular responsiveness associated with coarctation hypertension. Clin Exp Hypertens 19:297-312
Piascik, M T; Soltis, E E; Piascik, M M et al. (1996) Alpha-adrenoceptors and vascular regulation: molecular, pharmacologic and clinical correlates. Pharmacol Ther 72:215-41
Piascik, M T; Guarino, R D; Smith, M S et al. (1995) The specific contribution of the novel alpha-1D adrenoceptor to the contraction of vascular smooth muscle. J Pharmacol Exp Ther 275:1583-9
Piascik, M T; Smith, M S; Soltis, E E et al. (1994) Identification of the mRNA for the novel alpha 1D-adrenoceptor and two other alpha 1-adrenoceptors in vascular smooth muscle. Mol Pharmacol 46:30-40
Soltis, E E; Newman, P S; Olson, J W (1994) Eflornithine treatment in SHR: potential role of vascular polyamines and ornithine decarboxylase in hypertension. Clin Exp Hypertens 16:595-610
Piascik, M T; Smith, M S; Barron, K W et al. (1993) The regulation of regional hemodynamics by alpha-1 adrenoceptor subtypes in the conscious rat. J Pharmacol Exp Ther 267:1250-5