Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
5R29HL048848-05
Application #
2224944
Study Section
Cardiovascular and Renal Study Section (CVB)
Project Start
1992-08-01
Project End
1997-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
5
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Brigham Young University
Department
Chemistry
Type
Schools of Arts and Sciences
DUNS #
City
Provo
State
UT
Country
United States
Zip Code
84602
Belevych, Andriy E; Sansom, Sarah E; Terentyeva, Radmila et al. (2011) MicroRNA-1 and -133 increase arrhythmogenesis in heart failure by dissociating phosphatase activity from RyR2 complex. PLoS One 6:e28324
Nishijima, Yoshinori; Sridhar, Arun; Bonilla, Ingrid et al. (2011) Tetrahydrobiopterin depletion and NOS2 uncoupling contribute to heart failure-induced alterations in atrial electrophysiology. Cardiovasc Res 91:71-9
Elton, Terry S; Martin, Mickey M; Sansom, Sarah E et al. (2011) miRNAs got rhythm. Life Sci 88:373-83
Feldman, David; Elton, Terry S; Menachemi, Doron M et al. (2010) Heart rate control with adrenergic blockade: clinical outcomes in cardiovascular medicine. Vasc Health Risk Manag 6:387-97
Kuhn, Donald E; Nuovo, Gerard J; Terry Jr, Alvin V et al. (2010) Chromosome 21-derived microRNAs provide an etiological basis for aberrant protein expression in human Down syndrome brains. J Biol Chem 285:1529-43
Elton, Terry S; Sansom, Sarah E; Martin, Mickey M (2010) Trisomy-21 gene dosage over-expression of miRNAs results in the haploinsufficiency of specific target proteins. RNA Biol 7:540-7
Sansom, Sarah E; Nuovo, Gerard J; Martin, Mickey M et al. (2010) miR-802 regulates human angiotensin II type 1 receptor expression in intestinal epithelial C2BBe1 cells. Am J Physiol Gastrointest Liver Physiol 299:G632-42