Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
5R29HL048920-04
Application #
2225031
Study Section
Experimental Cardiovascular Sciences Study Section (ECS)
Project Start
1993-05-01
Project End
1997-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost
Name
City of Hope National Medical Center
Department
Type
DUNS #
City
Duarte
State
CA
Country
United States
Zip Code
91010
Yerneni, K K; Bai, W; Khan, B V et al. (1999) Hyperglycemia-induced activation of nuclear transcription factor kappaB in vascular smooth muscle cells. Diabetes 48:855-64
Goalstone, M L; Natarajan, R; Standley, P R et al. (1998) Insulin potentiates platelet-derived growth factor action in vascular smooth muscle cells. Endocrinology 139:4067-72
Natarajan, R; Bai, W; Lanting, L et al. (1997) Effects of high glucose on vascular endothelial growth factor expression in vascular smooth muscle cells. Am J Physiol 273:H2224-31
Natarajan, R; Rosdahl, J; Gonzales, N et al. (1997) Regulation of 12-lipoxygenase by cytokines in vascular smooth muscle cells. Hypertension 30:873-9
Wen, Y; Nadler, J L; Gonzales, N et al. (1996) Mechanisms of ANG II-induced mitogenic responses: role of 12-lipoxygenase and biphasic MAP kinase. Am J Physiol 271:C1212-20
Natarajan, R; Bai, W; Rangarajan, V et al. (1996) Platelet-derived growth factor BB mediated regulation of 12-lipoxygenase in porcine aortic smooth muscle cells. J Cell Physiol 169:391-400
Natarajan, R; Lanting, L; Gonzales, N et al. (1996) Formation of an F2-isoprostane in vascular smooth muscle cells by elevated glucose and growth factors. Am J Physiol 271:H159-65
Gu, J L; Veerapanane, D; Rossi, J et al. (1995) Ribozyme-mediated inhibition of expression of leukocyte-type 12-lipoxygenase in porcine aortic vascular smooth muscle cells. Circ Res 77:14-20
Kim, J A; Gu, J L; Natarajan, R et al. (1995) A leukocyte type of 12-lipoxygenase is expressed in human vascular and mononuclear cells. Evidence for upregulation by angiotensin II. Arterioscler Thromb Vasc Biol 15:942-8
Natarajan, R; Bai, W; Gu, J et al. (1995) Regulation of 12-lipoxygenase by platelet-derived growth factor in vascular smooth muscle cells. Adv Prostaglandin Thromboxane Leukot Res 23:435-7

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