Depression in children and adolescents occurs in significant proportions, particularly among offspring of depressed parents, and is associated with suicide, academic and social difficulties, and increased risk of future depressions. The purpose of this study is to explore the parenting, cognitive, and stress factors associated with the development of depression during the early adolescent years. According to the Family Cognitive Diathesis Stress (FCDS) Model, when faced with an important negative life event, individuals who have a particular cognitive style (i.e., the propensity to make internal, stable, and global attributions and to develop negative expectations about the future) are more likely to become depressed. It is further hypothesized that this """"""""depressogenic"""""""" cognitive style has its origins in parent-child relationships characterized by criticism, rejection, and overcontrol. This depresssogenic cognitive style is hypothesized to mediate the relation between negative family interactions and the onset and maintenance of depression. This study will examine the validity of the FCDS model for understanding individual differences in children's reactions to negative life events as well as to the normative life experience of the transition into junior high school. Using a prospective longitudinal design, 250 children will be followed over the early adolescent years (grades 5 to 8). Children will be selected as being either """"""""high' or 'low' risk for developing depression based upon the history of depression in their parents. The primary variables to be assessed are: cognitions (e.g., attributions, expectancies), family factors (e.g., parenting style, family conflict), life events, and social support. Pubertal development, depression and other symptomatology also will be monitored. Multiple regression analyses will be used to test the primary hypotheses concerning the interaction between cognitions and stress in the prediction of depression, and the role of children's cognitive style as a potential mediator between parenting characteristics and depression in children. The study also will explore the family, stress, and cognitive factors associated with the increased rate of depression over the early adolescent years. This research has important implications for understanding the processes underlying individual differences in the development of depression particularly among """"""""high risk"""""""" offspring, and will serve as a guide for the development of programs aimed at ameliorating and preventing the onset of depression in children and adults in the future.

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
5R29MH045458-03
Application #
3475300
Study Section
Psychopathology and Clinical Biology Research Review Committee (PCB)
Project Start
1991-04-01
Project End
1996-03-31
Budget Start
1993-05-01
Budget End
1994-03-31
Support Year
3
Fiscal Year
1993
Total Cost
Indirect Cost
Name
Vanderbilt University Medical Center
Department
Type
Schools of Education
DUNS #
004413456
City
Nashville
State
TN
Country
United States
Zip Code
37212
Kim Park, Irene J; Garber, Judy; Ciesla, Jeffrey A et al. (2008) Convergence among multiple methods of measuring positivity and negativity in the family environment: relation to depression in mothers and their children. J Fam Psychol 22:123-34
Bohnert, Amy M; Garber, Judy (2007) Prospective relations between organized activity participation and psychopathology during adolescence. J Abnorm Child Psychol 35:1021-33
Bohon, Cara; Garber, Judy; Horowitz, Jason L (2007) Predicting school dropout and adolescent sexual behavior in offspring of depressed and nondepressed mothers. J Am Acad Child Adolesc Psychiatry 46:15-24
Little, Stephanie A; Garber, Judy (2005) The role of social stressors and interpersonal orientation in explaining the longitudinal relation between externalizing and depressive symptoms. J Abnorm Psychol 114:432-43
Tomarken, Andrew J; Dichter, Gabriel S; Garber, Judy et al. (2004) Resting frontal brain activity: linkages to maternal depression and socio-economic status among adolescents. Biol Psychol 67:77-102
Nolan, Susan A; Flynn, Cynthia; Garber, Judy (2003) Prospective relations between rejection and depression in young adolescents. J Pers Soc Psychol 85:745-55
Kaminski, Kathleen M; Garber, Judy (2002) Depressive spectrum disorders in high-risk adolescents: episode duration and predictors of time to recovery. J Am Acad Child Adolesc Psychiatry 41:410-8
Ellis, B J; Garber, J (2000) Psychosocial antecedents of variation in girls' pubertal timing: maternal depression, stepfather presence, and marital and family stress. Child Dev 71:485-501
Garber, J; Little, S; Hilsman, R et al. (1998) Family predictors of suicidal symptoms in young adolescents. J Adolesc 21:445-57
Zeman, J; Garber, J (1996) Display rules for anger, sadness, and pain: it depends on who is watching. Child Dev 67:957-73

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