Sequential Events in Neurite Outgrowth and Stabilization

Shea, Thomas B.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Mental Health (NIMH)
• Type: First Independent Research Support & Transition (FIRST) Awards (R29)
• Project #: 5R29MH047349-05
• Application #: 2247568
• Study Section: Neurosciences Research Review Committee (BPN)
• Project Start: 1992-04-01
• Project End: 1997-03-31
• Budget Start: 1996-04-01
• Budget End: 1997-03-31
• Support Year: 5
• Fiscal Year: 1996

Institution

• Name: University of Massachusetts Lowell
• Department: Biology
• Type: Schools of Arts and Sciences
• DUNS #: 956072490
• City: Lowell
• State: MA
• Country: United States
• Zip Code: 01854

Publications

Shea, T B (1994) Delivery of anti-GAP-43 antibodies into neuroblastoma cells reduces growth cone size. Biochem Biophys Res Commun 203:459-64

Shea, T B; Beermann, M L (1994) Respective roles of neurofilaments, microtubules, MAP1B, and tau in neurite outgrowth and stabilization. Mol Biol Cell 5:863-75

Shea, T B (1994) Triton-soluble phosphovariants of the high molecular weight neurofilament subunit from NB2a/d1 cells are assembly-competent. Implications for normal and abnormal neurofilament assembly. FEBS Lett 343:131-6

Shea, T B; Beermann, M L (1993) Evidence that the monoclonal antibodies SMI-31 and SMI-34 recognize different phosphorylation-dependent epitopes of the murine high molecular mass neurofilament subunit. J Neuroimmunol 44:117-21

Shea, T B; Beermann, M L; Fischer, I (1993) Transient requirement for vimentin in neuritogenesis: intracellular delivery of anti-vimentin antibodies and antisense oligonucleotides inhibit neurite initiation but not elongation of existing neurites in neuroblastoma. J Neurosci Res 36:66-76

Shea, T B; Paskevich, P A; Beermann, M L (1993) The protein phosphatase inhibitor okadaic acid increases axonal neurofilaments and neurite caliber, and decreases axonal microtubules in NB2a/d1 cells. J Neurosci Res 35:507-21