Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
5R29MH048866-06
Application #
2033900
Study Section
Neurosciences Research Review Committee (BPN)
Project Start
1992-09-30
Project End
1998-03-31
Budget Start
1996-09-30
Budget End
1998-03-31
Support Year
6
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Tennessee Health Science Center
Department
Neurology
Type
Schools of Medicine
DUNS #
941884009
City
Memphis
State
TN
Country
United States
Zip Code
38163
Chung, Sangmi; Moon, Jisook; Kim, Kwang-Soo (2014) Improvement of neurological dysfunctions in aphakia mice, a model of Parkinson's disease, after transplantation of ES cell-derived dopaminergic neuronal precursors. Methods Mol Biol 1213:285-91
Kim, Tae-Gon; Yao, Ruiqin; Monnell, Travis et al. (2014) Efficient specification of interneurons from human pluripotent stem cells by dorsoventral and rostrocaudal modulation. Stem Cells 32:1789-804
Kim, Kyoung-Shim; Kang, Young-Mi; Kang, Young et al. (2014) Pitx3 deficient mice as a genetic animal model of co-morbid depressive disorder and parkinsonism. Brain Res 1552:72-81
Hong, Sunghoi; Chung, Sangmi; Leung, Kaka et al. (2014) Functional roles of Nurr1, Pitx3, and Lmx1a in neurogenesis and phenotype specification of dopamine neurons during in vitro differentiation of embryonic stem cells. Stem Cells Dev 23:477-87
Moon, Jisook; Lee, Hyun-Seob; Kang, Jun Mo et al. (2013) Stem cell grafting improves both motor and cognitive impairments in a genetic model of Parkinson's disease, the aphakia (ak) mouse. Cell Transplant 22:1263-79
Chung, Sangmi; Kim, Chun-Hyung; Kim, Kwang-Soo (2012) Lmx1a regulates dopamine transporter gene expression during ES cell differentiation and mouse embryonic development. J Neurochem 122:244-50
Vasudevan, Anju; Won, Chungkil; Li, Suyan et al. (2012) Dopaminergic neurons modulate GABA neuron migration in the embryonic midbrain. Development 139:3136-41
Morrison, Brad E; Marcondes, Maria Cecilia Garibaldi; Nomura, Daniel K et al. (2012) Cutting edge: IL-13R?1 expression in dopaminergic neurons contributes to their oxidative stress-mediated loss following chronic peripheral treatment with lipopolysaccharide. J Immunol 189:5498-502
Chung, Sangmi; Moon, Jung-Il; Leung, Amanda et al. (2011) ES cell-derived renewable and functional midbrain dopaminergic progenitors. Proc Natl Acad Sci U S A 108:9703-8
Hong, Seok Jong; Huh, Yang Hoon; Leung, Amanda et al. (2011) Transcription factor AP-2? regulates the neurotransmitter phenotype and maturation of chromaffin cells. Mol Cell Neurosci 46:245-51

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