Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
1R29MH055724-01
Application #
2256072
Study Section
Molecular, Cellular, and Developmental Neurobiology Review Committee (MCDN)
Project Start
1996-08-01
Project End
2001-04-30
Budget Start
1996-08-01
Budget End
1997-04-30
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Texas A&M University
Department
Anatomy/Cell Biology
Type
Schools of Medicine
DUNS #
City
College Station
State
TX
Country
United States
Zip Code
77845
Cheema, Zulfiqar F; Santillano, Daniel R; Wade, Stephen B et al. (2004) The extracellular matrix, p53 and estrogen compete to regulate cell-surface Fas/Apo-1 suicide receptor expression in proliferating embryonic cerebral cortical precursors, and reciprocally, Fas-ligand modifies estrogen control of cell-cycle proteins. BMC Neurosci 5:11
Cheema, Z F; West, J R; Miranda, R C (2000) Ethanol induces Fas/Apo [apoptosis]-1 mRNA and cell suicide in the developing cerebral cortex. Alcohol Clin Exp Res 24:535-43
McAlhany Jr, R E; West, J R; Miranda, R C (2000) Glial-derived neurotrophic factor (GDNF) prevents ethanol-induced apoptosis and JUN kinase phosphorylation. Brain Res Dev Brain Res 119:209-16
McAlhany Jr, R E; Miranda, R C; Finnell, R H et al. (1999) Ethanol decreases Glial-Derived Neurotrophic Factor (GDNF) protein release but not mRNA expression and increases GDNF-stimulated Shc phosphorylation in the developing cerebellum. Alcohol Clin Exp Res 23:1691-7
Wade, S B; Oommen, P; Conner, W C et al. (1999) Overlapping and divergent actions of estrogen and the neurotrophins on cell fate and p53-dependent signal transduction in conditionally immortalized cerebral cortical neuroblasts. J Neurosci 19:6994-7006
Cheema, Z F; Wade, S B; Sata, M et al. (1999) Fas/Apo [apoptosis]-1 and associated proteins in the differentiating cerebral cortex: induction of caspase-dependent cell death and activation of NF-kappaB. J Neurosci 19:1754-70
McAlhany Jr, R E; West, J R; Miranda, R C (1997) Glial-derived neurotrophic factor rescues calbindin-D28k-immunoreactive neurons in alcohol-treated cerebellar explant cultures. J Neurobiol 33:835-47