Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
5R29NS029095-05
Application #
2267390
Study Section
Immunological Sciences Study Section (IMS)
Project Start
1991-02-01
Project End
1997-01-31
Budget Start
1995-02-01
Budget End
1997-01-31
Support Year
5
Fiscal Year
1995
Total Cost
Indirect Cost

  Institution

Name
Cleveland Clinic Lerner
Department
Type
DUNS #
017730458
City
Cleveland
State
OH
Country
United States
Zip Code
44195

  Publications

Glabinski, A R; Tuohy, V K; Ransohoff, R M (1998) Expression of chemokines RANTES, MIP-1alpha and GRO-alpha correlates with inflammation in acute experimental autoimmune encephalomyelitis. Neuroimmunomodulation 5:166-71
Tani, M; Glabinski, A R; Tuohy, V K et al. (1996) In situ hybridization analysis of glial fibrillary acidic protein mRNA reveals evidence of biphasic astrocyte activation during acute experimental autoimmune encephalomyelitis. Am J Pathol 148:889-96
Yu, M; Nishiyama, A; Trapp, B D et al. (1996) Interferon-beta inhibits progression of relapsing-remitting experimental autoimmune encephalomyelitis. J Neuroimmunol 64:91-100
Yu, M; Johnson, J M; Tuohy, V K (1996) Generation of autonomously pathogenic neo-autoreactive Th1 cells during the development of the determinant spreading cascade in murine autoimmune encephalomyelitis. J Neurosci Res 45:463-70
Yu, M; Johnson, J M; Tuohy, V K (1996) A predictable sequential determinant spreading cascade invariably accompanies progression of experimental autoimmune encephalomyelitis: a basis for peptide-specific therapy after onset of clinical disease. J Exp Med 183:1777-88
Glabinski, A R; Tani, M; Aras, S et al. (1995) Regulation and function of central nervous system chemokines. Int J Dev Neurosci 13:153-65
Tuohy, V K; Thomas, D M (1995) Sequence 104-117 of myelin proteolipid protein is a cryptic encephalitogenic T cell determinant for SJL/J mice. J Neuroimmunol 56:161-70
Tuohy, V K; Thomas, D M; Haqqi, T et al. (1995) Determinant-regulated onset of experimental autoimmune encephalomyelitis: distinct epitopes of myelin proteolipid protein mediate either acute or delayed disease in SJL/J mice. Autoimmunity 21:203-14
Glabinski, A R; Tani, M; Tuohy, V K et al. (1995) Central nervous system chemokine mRNA accumulation follows initial leukocyte entry at the onset of acute murine experimental autoimmune encephalomyelitis. Brain Behav Immun 9:315-30
Ransohoff, R M; Tuohy, V; Lehmann, P (1994) The immunology of multiple sclerosis: new intricacies and new insights. Curr Opin Neurol 7:242-9

Showing the most recent 10 out of 15 publications