Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
5R29NS029804-05
Application #
2267907
Study Section
Physiology Study Section (PHY)
Program Officer
Kitt, Cheryl A
Project Start
1991-07-20
Project End
1997-06-30
Budget Start
1995-07-01
Budget End
1997-06-30
Support Year
5
Fiscal Year
1995
Total Cost
Indirect Cost
Name
University of Pittsburgh
Department
Pharmacology
Type
Schools of Medicine
DUNS #
053785812
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213
Fomina, A F; Levitan, E S; Takimoto, K (1996) Dexamethasone rapidly increases calcium channel subunit messenger RNA expression and high voltage-activated calcium current in clonal pituitary cells. Neuroscience 72:857-62
Takimoto, K; Levitan, E S (1996) Altered K+ channel subunit composition following hormone induction of Kv1.5 gene expression. Biochemistry 35:14149-56
Fass, D M; Levitan, E S (1996) Bay K 8644 reveals two components of L-type Ca2+ channel current in clonal rat pituitary cells. J Gen Physiol 108:1-11
Fass, D M; Levitan, E S (1996) L-type Ca2+ channels access multiple open states to produce two components of Bay K 8644-dependent current in GH3 cells. J Gen Physiol 108:13-26
Levitan, E S; Gealy, R; Trimmer, J S et al. (1995) Membrane depolarization inhibits Kv1.5 voltage-gated K+ channel gene transcription and protein expression in pituitary cells. J Biol Chem 270:6036-41
Takimoto, K; Gealy, R; Levitan, E S (1995) Multiple protein kinases are required for basal Kv1.5 K+ channel gene expression in GH3 clonal pituitary cells. Biochim Biophys Acta 1265:22-8
Takimoto, K; Gealy, R; Fomina, A F et al. (1995) Inhibition of voltage-gated K+ channel gene expression by the neuropeptide thyrotropin-releasing hormone. J Neurosci 15:449-57
Fomina, A F; Levitan, E S (1995) Three phases of TRH-induced facilitation of exocytosis by single lactotrophs. J Neurosci 15:4982-91
Kramer, R H; Mokkapatti, R; Levitan, E S (1994) Effects of caffeine on intracellular calcium, calcium current and calcium-dependent potassium current in anterior pituitary GH3 cells. Pflugers Arch 426:12-20
Takimoto, K; Levitan, E S (1994) Glucocorticoid induction of Kv1.5 K+ channel gene expression in ventricle of rat heart. Circ Res 75:1006-13

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