Factors Enhancing and Impairing Dopamine Grafts

Yurek, David M.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Neurological Disorders and Stroke (NINDS)
• Type: First Independent Research Support & Transition (FIRST) Awards (R29)
• Project #: 5R29NS029994-04
• Application #: 2268065
• Study Section: Neurology B Subcommittee 2 (NEUB)
• Project Start: 1993-01-15
• Project End: 1997-12-31
• Budget Start: 1996-01-01
• Budget End: 1996-12-31
• Support Year: 4
• Fiscal Year: 1996

Institution

• Name: University of Kentucky
• Department: Surgery
• Type: Schools of Medicine
• DUNS #: 832127323
• City: Lexington
• State: KY
• Country: United States
• Zip Code: 40506

Publications

Yurek, D M (1998) Glial cell line-derived neurotrophic factor improves survival of dopaminergic neurons in transplants of fetal ventral mesencephalic tissue. Exp Neurol 153:195-202

Yurek, D M; Hipkens, S B; Wiegand, S J et al. (1998) Optimal effectiveness of BDNF for fetal nigral transplants coincides with the ontogenic appearance of BDNF in the striatum. J Neurosci 18:6040-7

Yurek, D M (1997) Intranigral transplants of fetal ventral mesencephalic tissue attenuate D1-agonist-induced rotational behavior. Exp Neurol 143:1-9

Yurek, D M; Lu, W; Hipkens, S et al. (1996) BDNF enhances the functional reinnervation of the striatum by grafted fetal dopamine neurons. Exp Neurol 137:105-18

Prasad, M R; Ramaiah, C; McIntosh, T K et al. (1994) Regional levels of lactate and norepinephrine after experimental brain injury. J Neurochem 63:1086-94

Yurek, D M; Hipkens, S B (1994) Intranigral injections of SCH 23390 inhibit SKF 82958-induced rotational behavior. Brain Res 639:329-32

Yurek, D M; Hipkens, S B (1993) Intranigral injections of SCH 23390 inhibit amphetamine-induced rotational behavior. Brain Res 623:56-64