Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
5R29NS034373-02
Application #
2273584
Study Section
Neurology B Subcommittee 2 (NEUB)
Project Start
1995-08-01
Project End
2000-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Pennsylvania
Department
Biology
Type
Schools of Arts and Sciences
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
Dorsey, Susan G; Bambrick, Linda L; Balice-Gordon, Rita J et al. (2002) Failure of brain-derived neurotrophic factor-dependent neuron survival in mouse trisomy 16. J Neurosci 22:2571-8
Chang, Q; Pereda, A; Pinter, M J et al. (2000) Nerve injury induces gap junctional coupling among axotomized adult motor neurons. J Neurosci 20:674-84
Balice-Gordon, R J; Smith, D B; Goldman, J et al. (2000) Functional motor unit failure precedes neuromuscular degeneration in canine motor neuron disease. Ann Neurol 47:596-605
Chang, Q; Balice-Gordon, R J (2000) Gap junctional communication among developing and injured motor neurons. Brain Res Brain Res Rev 32:242-9
O'Malley, J P; Waran, M T; Balice-Gordon, R J (1999) In vivo observations of terminal Schwann cells at normal, denervated, and reinnervated mouse neuromuscular junctions. J Neurobiol 38:270-86
Gonzalez, M; Ruggiero, F P; Chang, Q et al. (1999) Disruption of Trkb-mediated signaling induces disassembly of postsynaptic receptor clusters at neuromuscular junctions. Neuron 24:567-83
Chang, Q; Gonzalez, M; Pinter, M J et al. (1999) Gap junctional coupling and patterns of connexin expression among neonatal rat lumbar spinal motor neurons. J Neurosci 19:10813-28
Balice-Gordon, R J; Bone, L J; Scherer, S S (1998) Functional gap junctions in the schwann cell myelin sheath. J Cell Biol 142:1095-104
Woo, Y J; Raju, G P; Swain, J L et al. (1997) In utero cardiac gene transfer via intraplacental delivery of recombinant adenovirus. Circulation 96:3561-9