Pressure to improye quality and lower cost of health care has stimulated the evaluation of the effectiveness of medical interventions, such as gastrointestinal (GI) endoscopy. Despite widespread use of endoscopy in the diagnosis and treatment of GI diseases, very little is known about the utilization and effectiveness in community-based settings. The Clinical Outcomes Research Initiative (CORI) built a consortium of physicians who contribute data to a national endoscopic data repository to study outcomes of endoscopic procedures in diverse practice settings. These data have been used to study endoscopic utilization, frequency and severity of endoscopic findings, outcomes of endoscopic treatment, impact of endoscopy on quality of life and heath care utilization, new endoscopic innovations, adverse events associated with endoscopy, and natural history of chronic conditions. This project spans the interface of biomedical research and information technologies. CORI's success depends upon maintaining a consortium of practice-based clinicians who send data to the national repository. A large, diverse consortium allows the study of effectiveness of endoscopy in """"""""real life"""""""" practice. In Phase I of the project, all clinical affiliates use a computerized report generator developed specifically for the project. In Phase II, interfaces will be created to capture endoscopic data from other computerized report generators, image management systems, and non-endoscopic data from electronic records while maintaining quality control and preserving patient privacy. These enhancements will enrich the data repository and enhance effectiveness research. The primary goal of this proposal is to use information technologies to enhance CORI's research mission through: Expansion of participation in CORI to users of commercial software, Incorporation of non-endoscopic data into the endoscopic database, Enhancement of consortium-building with novel methods of member communication, Acquisition of endoscopic images for research and validation of terminology.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Exploratory/Developmental Grants Phase II (R33)
Project #
5R33DK061778-02
Application #
6625985
Study Section
Special Emphasis Panel (ZRG1-SSS-9 (41))
Program Officer
Everhart, James
Project Start
2002-05-01
Project End
2005-04-30
Budget Start
2003-05-01
Budget End
2004-04-30
Support Year
2
Fiscal Year
2003
Total Cost
$400,549
Indirect Cost
Name
Oregon Health and Science University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
096997515
City
Portland
State
OR
Country
United States
Zip Code
97239
Mooers, Harrison M; Holub, Jennifer L; Lieberman, David A (2018) Screening Women Aged 50-59 for CRC Using Fecal Occult Blood Test Produces Outcomes Similar to Men Undergoing Screening Colonoscopy. Dig Dis Sci 63:2780-2785
Kluge, Matthew A; Williams, J Lucas; Wu, Connie K et al. (2018) Inadequate Boston Bowel Preparation Scale scores predict the risk of missed neoplasia on the next colonoscopy. Gastrointest Endosc 87:744-751
Holub, Jennifer L; Morris, Cynthia; Fagnan, Lyle J et al. (2018) Quality of Colonoscopy Performed in Rural Practice: Experience From the Clinical Outcomes Research Initiative and the Oregon Rural Practice-Based Research Network. J Rural Health 34 Suppl 1:s75-s83
Woodward, Zibing; Williams, J Lucas; Sonnenberg, Amnon (2016) Length of endoscopic workup in gastrointestinal bleeding. Eur J Gastroenterol Hepatol 28:1166-71
Saks, Karen; Enestvedt, Brintha K; Holub, Jennifer L et al. (2016) Colonoscopy Identifies Increased Prevalence of Large Polyps or Tumors in Patients 40-49 Years Old With Hematochezia vs Other Gastrointestinal Indications. Clin Gastroenterol Hepatol 14:843-849
Day, Lukejohn W; Nazareth, Michelle; Sewell, Justin L et al. (2015) Practice variation in PEG tube placement: trends and predictors among providers in the United States. Gastrointest Endosc 82:37-45
Childers, Ryan E; Williams, J Lucas; Sonnenberg, Amnon (2015) Practice patterns of sedation for colonoscopy. Gastrointest Endosc 82:503-11
Lieberman, David A; Williams, J Lucas; Holub, Jennifer L et al. (2014) Colonoscopy utilization and outcomes 2000 to 2011. Gastrointest Endosc 80:133-43
Bielawska, Barbara; Day, Andrew G; Lieberman, David A et al. (2014) Risk factors for early colonoscopic perforation include non-gastroenterologist endoscopists: a multivariable analysis. Clin Gastroenterol Hepatol 12:85-92
Calderwood, Audrey H; Logan, Judith R; Zurfluh, Michael et al. (2014) Validity of a Web-based educational program to disseminate a standardized bowel preparation rating scale. J Clin Gastroenterol 48:856-61

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