We have shown that type 2 diabetes mellitus affects approximately 18% of Arab Americans 20-75 years of age. Impaired fasting glucose (IFG) or impaired glucose tolerance (IGT) are also present in 23% of this population. Previous studies have demonstrated that lifestyle interventions can delay or prevent the development of type 2 diabetes in high-risk persons with IGT. However, there may be barriers to implementing these interventions in this culturally unique community. ? Our long-term goal is to prevent type 2 diabetes in the high-risk Arab-American population. The objective of this planning grant is to demonstrate the feasibility of a community-based, culturally specific lifestyle intervention for diabetes prevention.
The aims of this study are: 1). to investigate the effects of an educational intervention targeting knowledge and health beliefs on willingness to engage in and complete a diabetes prevention intervention, and 2). to determine the feasibility and acceptability of a community-based and culturally-specific lifestyle intervention aimed at diabetes prevention. This study will also provide pilot data needed to design a future large-scale clinical trial aimed at reducing the burden of diabetes in this community. Approximately 100 Arab American individuals = 30 years of age and with a BMI = 27 kg/m2 will be invited to participate in the lifestyle intervention. Those unwilling to participate will be invited to participate in an education program and their willingness to participate in the lifestyle intervention will be re-examined. Based on our preliminary data, we designed a modified version of the lifestyle intervention of the Diabetes Prevention Program prototype. Qualitative methods including focus groups and health belief surveys will be used to identify the barriers and facilitators to diabetes prevention translational interventions. Adherence to scheduled activities and changes in body weight, diet and physical activity will also be assessed. ? ?

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Planning Grant (R34)
Project #
1R34DK076663-01A1
Application #
7305650
Study Section
Special Emphasis Panel (ZDK1-GRB-1 (M1))
Program Officer
Garfield, Sanford A
Project Start
2007-09-01
Project End
2009-08-31
Budget Start
2007-09-01
Budget End
2008-08-31
Support Year
1
Fiscal Year
2007
Total Cost
$239,357
Indirect Cost
Name
Wayne State University
Department
Public Health & Prev Medicine
Type
Schools of Pharmacy
DUNS #
001962224
City
Detroit
State
MI
Country
United States
Zip Code
48202
Bertran, Elizabeth A; Pinelli, Nicole R; Sills, Stephen J et al. (2017) The Arab American experience with diabetes: Perceptions, myths and implications for culturally-specific interventions. Prim Care Diabetes 11:13-19
Pinelli, Nicole R; Brown, Morton B; Herman, William H et al. (2011) Family support is associated with success in achieving weight loss in a group lifestyle intervention for diabetes prevention in Arab Americans. Ethn Dis 21:480-4
Jaber, Linda A; Pinelli, Nicole R; Brown, Morton B et al. (2011) Feasibility of group lifestyle intervention for diabetes prevention in Arab Americans. Diabetes Res Clin Pract 91:307-15
Pinelli, Nicole R; Herman, William H; Brown, Morton B et al. (2010) Perceived risk and the willingness to enroll in a diabetes prevention lifestyle intervention in Arab-Americans. Diabetes Res Clin Pract 90:e27-9