Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Unknown (R35)
Project #
3R35CA042510-02S1
Application #
3479349
Study Section
(SRC)
Project Start
1986-07-01
Project End
1993-06-30
Budget Start
1987-07-01
Budget End
1988-06-30
Support Year
2
Fiscal Year
1988
Total Cost
Indirect Cost
Name
Indiana University-Purdue University at Indianapolis
Department
Type
Schools of Medicine
DUNS #
005436803
City
Indianapolis
State
IN
Country
United States
Zip Code
46202
Look, K Y; Moore, D H; Sutton, G P et al. (1997) Increased thymidine kinase and thymidylate synthase activities in human epithelial ovarian carcinoma. Anticancer Res 17:2353-6
Vitale, M; Zamai, L; Falcieri, E et al. (1997) IMP dehydrogenase inhibitor, tiazofurin, induces apoptosis in K562 human erythroleukemia cells. Cytometry 30:61-6
Olah, E; Csokay, B; Prajda, N et al. (1996) Molecular mechanisms in the antiproliferative action of taxol and tiazofurin. Anticancer Res 16:2469-77
Zamai, L; Zauli, G; Bavelloni, A et al. (1995) Tiazofurin induces a down-modulation of ICAM-1 expression on K562 target cells impairing NK adhesion and killing. Cell Immunol 164:100-4
Singhal, R L; Yeh, Y A; Look, K Y et al. (1994) Coordinated increase in activities of the signal transduction enzymes PI kinase and PIP kinase in human cancer cells. Life Sci 55:1487-92
Rizzo, M T; Weber, G (1994) 1-Phosphatidylinositol 4-kinase: an enzyme linked with proliferation and malignancy. Cancer Res 54:2611-4
Weber, G; Hata, Y; Prajda, N (1994) Role of differentiation induction in action of purine antimetabolites. Pharm World Sci 16:77-83
Hata, Y; Sandler, A; Loehrer, P J et al. (1994) Synergism of taxol and gallium nitrate in human breast carcinoma cells: schedule dependency. Oncol Res 6:19-24
Weber, G; Prajda, N (1994) Targeted and non-targeted actions of anti-cancer drugs. Adv Enzyme Regul 34:71-89
Yeh, Y A; Olah, E; Wendel, J J et al. (1994) Synergistic action of taxol with tiazofurin and methotrexate in human breast cancer cells: schedule-dependence. Life Sci 54:PL431-5

Showing the most recent 10 out of 78 publications