Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Unknown (R35)
Project #
3R35CA053893-06S1
Application #
2831102
Study Section
Special Emphasis Panel (SRC (88))
Program Officer
Johnson, George S
Project Start
1993-05-14
Project End
2000-02-29
Budget Start
1998-03-01
Budget End
1999-02-28
Support Year
6
Fiscal Year
1998
Total Cost
Indirect Cost
Name
Fox Chase Cancer Center
Department
Type
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19111
Findlay, Victoria J; Townsend, Danyelle M; Saavedra, Joseph E et al. (2004) Tumor cell responses to a novel glutathione S-transferase-activated nitric oxide-releasing prodrug. Mol Pharmacol 65:1070-9
Vulevic, B; Chen, Z; Boyd, J T et al. (2001) Cloning and characterization of human adenosine 5'-triphosphate-binding cassette, sub-family A, transporter 2 (ABCA2). Cancer Res 61:3339-47
Shen, H; Chen, Z J; Zilfou, J T et al. (2001) Binding of the aminothiol WR-1065 to transcription factors influences cellular response to anticancer drugs. J Pharmacol Exp Ther 297:1067-73
Ruscoe, J E; Rosario, L A; Wang, T et al. (2001) Pharmacologic or genetic manipulation of glutathione S-transferase P1-1 (GSTpi) influences cell proliferation pathways. J Pharmacol Exp Ther 298:339-45
O'Brien, M; Kruh, G D; Tew, K D (2000) The influence of coordinate overexpression of glutathione phase II detoxification gene products on drug resistance. J Pharmacol Exp Ther 294:480-7
Rosario, L A; O'Brien, M L; Henderson, C J et al. (2000) Cellular response to a glutathione S-transferase P1-1 activated prodrug. Mol Pharmacol 58:167-74
Ranganathan, S; Ciaccio, P J; Walsh, E S et al. (1999) Genomic sequence of human glyoxalase-I: analysis of promoter activity and its regulation. Gene 240:149-55
O'Brien, M L; Vulevic, B; Freer, S et al. (1999) Glutathione peptidomimetic drug modulator of multidrug resistance-associated protein. J Pharmacol Exp Ther 291:1348-55
Shen, H; Schultz, M P; Tew, K D (1999) Glutathione conjugate interactions with DNA-dependent protein kinase. J Pharmacol Exp Ther 290:1101-6
Laing, N M; Belinsky, M G; Kruh, G D et al. (1998) Amplification of the ATP-binding cassette 2 transporter gene is functionally linked with enhanced efflux of estramustine in ovarian carcinoma cells. Cancer Res 58:1332-7

Showing the most recent 10 out of 19 publications