Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37AA002666-20
Application #
2042977
Study Section
Special Emphasis Panel (NSS)
Project Start
1979-07-01
Project End
1998-08-31
Budget Start
1996-09-01
Budget End
1997-08-31
Support Year
20
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
Massachusetts General Hospital
Department
Type
DUNS #
City
Boston
State
MA
Country
United States
Zip Code
02199

  Publications

Derdak, Zoltan; Villegas, Kristine A; Wands, Jack R (2012) Early growth response-1 transcription factor promotes hepatic fibrosis and steatosis in long-term ethanol-fed Long-Evans rats. Liver Int 32:761-70
de la Monte, Suzanne; Derdak, Zoltan; Wands, Jack R (2012) Alcohol, insulin resistance and the liver-brain axis. J Gastroenterol Hepatol 27 Suppl 2:33-41
de la Monte, Suzanne M; Pang, Maoyin; Chaudhry, Rajeev et al. (2011) Peroxisome proliferator-activated receptor agonist treatment of alcohol-induced hepatic insulin resistance. Hepatol Res 41:386-98
Derdak, Zoltan; Lang, Charles H; Villegas, Kristine A et al. (2011) Activation of p53 enhances apoptosis and insulin resistance in a rat model of alcoholic liver disease. J Hepatol 54:164-72
de la Monte, Suzanne M; Wands, Jack R (2010) Role of central nervous system insulin resistance in fetal alcohol spectrum disorders. J Popul Ther Clin Pharmacol 17:e390-404
He, Jiman; de la Monte, Suzanne; Wands, Jack R (2010) The p85beta regulatory subunit of PI3K serves as a substrate for PTEN protein phosphatase activity during insulin mediated signaling. Biochem Biophys Res Commun 397:513-9
Szabo, Gyongyi; Wands, Jack R; Eken, Ahmet et al. (2010) Alcohol and hepatitis C virus--interactions in immune dysfunctions and liver damage. Alcohol Clin Exp Res 34:1675-86
de la Monte, Suzanne M; Neusner, Alexander; Chu, Jennifer et al. (2009) Epidemilogical trends strongly suggest exposures as etiologic agents in the pathogenesis of sporadic Alzheimer's disease, diabetes mellitus, and non-alcoholic steatohepatitis. J Alzheimers Dis 17:519-29
de la Monte, Suzanne M; Tong, Ming; Carlson, Rolf I et al. (2009) Ethanol inhibition of aspartyl-asparaginyl-beta-hydroxylase in fetal alcohol spectrum disorder: potential link to the impairments in central nervous system neuronal migration. Alcohol 43:225-40
de la Monte, Suzanne M; Longato, Lisa; Tong, Ming et al. (2009) Insulin resistance and neurodegeneration: roles of obesity, type 2 diabetes mellitus and non-alcoholic steatohepatitis. Curr Opin Investig Drugs 10:1049-60

Showing the most recent 10 out of 155 publications