Agency
National Institute of Health (NIH)
Institute
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
3R37AA005809-15S1
Application #
2043337
Study Section
Special Emphasis Panel (NSS)
Project Start
1982-07-01
Project End
1998-12-31
Budget Start
1996-01-01
Budget End
1996-12-31
Support Year
15
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Texas Austin
Department
Neurosciences
Type
Schools of Pharmacy
DUNS #
City
Austin
State
TX
Country
United States
Zip Code
78712
Morrow, A Leslie; Ferrani-Kile, Karima; Davis, Margaret I et al. (2004) Ethanol effects on cell signaling mechanisms. Alcohol Clin Exp Res 28:217-27
Nixon, Kimberly; Hughes, Peter D; Amsel, Abram et al. (2004) NMDA receptor subunit expression after combined prenatal and postnatal exposure to ethanol. Alcohol Clin Exp Res 28:105-12
Ferrani-Kile, K; Randall, P K; Leslie, S W (2003) Acute ethanol affects phosphorylation state of the NMDA receptor complex: implication of tyrosine phosphatases and protein kinase A. Brain Res Mol Brain Res 115:78-86
Brownson, Delia M; Mabry, Tom J; Leslie, Steven W (2002) The cycad neurotoxic amino acid, beta-N-methylamino-L-alanine (BMAA), elevates intracellular calcium levels in dissociated rat brain cells. J Ethnopharmacol 82:159-67
Nixon, Kimberly; Hughes, Peter D; Amsel, Abram et al. (2002) NMDA receptor subunit expression following early postnatal exposure to ethanol. Brain Res Dev Brain Res 139:295-9
Acquaah-Mensah, George K; Kehrer, James P; Leslie, Steven W (2002) In utero ethanol suppresses cerebellar activator protein-1 and nuclear factor-kappa B transcriptional activation in a rat fetal alcohol syndrome model. J Pharmacol Exp Ther 301:277-83
Hughes, P D; Wilson, W R; Leslie, S W (2001) Effect of gestational ethanol exposure on the NMDA receptor complex in rat forebrain: from gene transcription to cell surface. Brain Res Dev Brain Res 129:135-45
Acquaah-Mensah, G K; Leslie, S W; Kehrer, J P (2001) Acute exposure of cerebellar granule neurons to ethanol suppresses stress-activated protein kinase-1 and concomitantly induces AP-1. Toxicol Appl Pharmacol 175:10-8
Hughes, P D; Kim, Y N; Randall, P K et al. (1998) Effect of prenatal ethanol exposure on the developmental profile of the NMDA receptor subunits in rat forebrain and hippocampus. Alcohol Clin Exp Res 22:1255-61
Robichon, R; Randall, P K; Leslie, S W (1997) A partial agonist model used in the allosteric modulation of the NMDA receptor. Eur J Pharmacol 328:255-63

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