Regulation of Alcohol and Aldehyde Dehydrogenases

Crabb, David W.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute on Alcohol Abuse and Alcoholism (NIAAA)
• Type: Method to Extend Research in Time (MERIT) Award (R37)
• Project #: 2R37AA006434-08
• Application #: 2043466
• Study Section: Biochemistry, Physiology and Medicine Subcommittee (ALCB)
• Project Start: 1985-05-01
• Project End: 1996-04-30
• Budget Start: 1992-05-01
• Budget End: 1993-04-30
• Support Year: 8
• Fiscal Year: 1992

Institution

• Name: Indiana University-Purdue University at Indianapolis
• Department: Internal Medicine/Medicine
• Type: Schools of Medicine
• DUNS #: 005436803
• City: Indianapolis
• State: IN
• Country: United States
• Zip Code: 46202

Publications

Matsumoto, Michinaga; Cyganek, Izabela; Sanghani, Paresh C et al. (2011) Ethanol metabolism by HeLa cells transduced with human alcohol dehydrogenase isoenzymes: control of the pathway by acetaldehyde concentration. Alcohol Clin Exp Res 35:28-38

Crabb, David W (2004) Alcohol deranges hepatic lipid metabolism via altered transcriptional regulation. Trans Am Clin Climatol Assoc 115:273-87

Crabb, D W; Stewart, M J; Chan, R J (1996) Dexamethasone represses phorbol ester-, forskolin-, and calcium-stimulated expression of a preproenkephalin A promoter-chloramphenicol acetyltransferase gene via a receptor-mediated mechanism. Brain Res Mol Brain Res 42:103-8

Chan, R J; McBride, A W; Thomasson, H R et al. (1994) Allele frequencies of the preproenkephalin A (PENK) gene CA repeat in Asians, African-Americans, and Caucasians: lack of evidence for different allele frequencies in alcoholics. Alcohol Clin Exp Res 18:533-5