Wu, Defeng; Cederbaum, Arthur (2008) Cytochrome P4502E1 sensitizes to tumor necrosis factor alpha-induced liver injury through activation of mitogen-activated protein kinases in mice. Hepatology 47:1005-17
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Lu, Yongke; Gong, Pengfei; Cederbaum, Arthur I (2008) Pyrazole induced oxidative liver injury independent of CYP2E1/2A5 induction due to Nrf2 deficiency. Toxicology 252:9-16
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Lu, Yongke; Zhuge, Jian; Wang, Xiaodong et al. (2008) Cytochrome P450 2E1 contributes to ethanol-induced fatty liver in mice. Hepatology 47:1483-94
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Caro, Andres A; Cederbaum, Arthur I (2007) Role of intracellular calcium and phospholipase A2 in arachidonic acid-induced toxicity in liver cells overexpressing CYP2E1. Arch Biochem Biophys 457:252-63
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Kessova, Irina G; Cederbaum, Arthur I (2007) Mitochondrial alterations in livers of Sod1-/- mice fed alcohol. Free Radic Biol Med 42:1470-80
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Dey, Aparajita; Cederbaum, Arthur I (2007) Induction of cytochrome P450 2E1 [corrected] promotes liver injury in ob/ob mice. Hepatology 45:1355-65
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Wu, Defeng; Cederbaum, Arthur I (2006) Opposite action of S-adenosyl methionine and its metabolites on CYP2E1-mediated toxicity in pyrazole-induced rat hepatocytes and HepG2 E47 cells. Am J Physiol Gastrointest Liver Physiol 290:G674-84
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Caro, Andres A; Cederbaum, Arthur I (2006) Role of phosphatidylinositol 3-kinase/AKT as a survival pathway against CYP2E1-dependent toxicity. J Pharmacol Exp Ther 318:360-72
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Cederbaum, Arthur I (2006) Cytochrome P450 2E1-dependent oxidant stress and upregulation of anti-oxidant defense in liver cells. J Gastroenterol Hepatol 21 Suppl 3:S22-5
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Bai, Jingxiang; Cederbaum, Arthur I (2006) Adenovirus-mediated expression of CYP2E1 produces liver toxicity in mice. Toxicol Sci 91:365-71
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