The goal of this project is to determine, in the context of visual search and classification tasks, the degree of age-related change in different forms of attentional functioning. The project is also concerned with the potential contribution of mild essential hypertension to age-related cognitive changes. The proposed experiments will involve measuring subjects' reaction time and accuracy for decisions regarding different types of visual displays. Experiments 1-6 will test the hypothesis that, as perceptual load is increased, disruption of performance from task-irrelevant information (flankers) will decline more for young adults that for older adults. This hypothesis will be assessed under conditions of varying display size (Experiment 1), perceptual discriminability (Experiment 2) memory load (Experiment 3), target location predictability (Experiment 4), and response-correlated flankers (Experiments 5 and 6). Experiments 7-13 will investigate the allocation of attention. Experiments 7-8 will determine whether there is an age-related change in the spatial distribution of attention. Experiments 9-12 will use the subadditivity diagnostic and analysis of different levels of stochastic dominance to test a model in which the shift of attention between display positions is serial but distance-independent. Experiment 13 will examine age differences in the ability to guide search on the basis of target-relevant features. Experiment 14 will compare the performance of hypertensive and normotensive individuals in visual search performance, to test the hypothesis that the interaction between age and hypertensive status is related to the memory demands of the task. Data from the present project will contribute to an improved account of the age-related changes in attentional functioning in healthy individuals, and of the potential role of hypertension in age-related cognitive change.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37AG002163-18
Application #
6163760
Study Section
Special Emphasis Panel (ZRG2-HUD-2 (03))
Program Officer
Wagster, Molly V
Project Start
1980-04-01
Project End
2002-02-28
Budget Start
2000-03-01
Budget End
2001-02-28
Support Year
18
Fiscal Year
2000
Total Cost
$243,928
Indirect Cost
Name
Duke University
Department
Psychiatry
Type
Schools of Medicine
DUNS #
071723621
City
Durham
State
NC
Country
United States
Zip Code
27705
Bucur, Barbara; Madden, David J (2010) Effects of adult age and blood pressure on executive function and speed of processing. Exp Aging Res 36:153-68
Henninger, Debra E; Madden, David J; Huettel, Scott A (2010) Processing speed and memory mediate age-related differences in decision making. Psychol Aging 25:262-70
Costello, Matthew C; Madden, David J; Shepler, Anne M et al. (2010) Age-related preservation of top-down control over distraction in visual search. Exp Aging Res 36:249-72
Costello, Matthew C; Madden, David J; Mitroff, Stephen R et al. (2010) Age-related decline of visual processing components in change detection. Psychol Aging 25:356-68
Bucur, Barbara; Madden, David J; Spaniol, Julia et al. (2008) Age-related slowing of memory retrieval: contributions of perceptual speed and cerebral white matter integrity. Neurobiol Aging 29:1070-9
Madden, David J (2007) Aging and Visual Attention. Curr Dir Psychol Sci 16:70-74
Madden, David J; Spaniol, Julia; Whiting, Wythe L et al. (2007) Adult age differences in the functional neuroanatomy of visual attention: a combined fMRI and DTI study. Neurobiol Aging 28:459-76
Whiting, Wythe L; Madden, David J; Babcock, Katherine J (2007) Overriding age differences in attentional capture with top-down processing. Psychol Aging 22:223-32
Madden, David J; Spaniol, Julia; Bucur, Barbara et al. (2007) Age-related increase in top-down activation of visual features. Q J Exp Psychol (Colchester) 60:644-51
Daselaar, Sander M; Fleck, Mathias S; Dobbins, Ian G et al. (2006) Effects of healthy aging on hippocampal and rhinal memory functions: an event-related fMRI study. Cereb Cortex 16:1771-82

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