Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37AG004344-13
Application #
2048853
Study Section
Special Emphasis Panel (NSS)
Project Start
1984-01-01
Project End
1998-01-31
Budget Start
1996-03-05
Budget End
1998-01-31
Support Year
13
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Texas Sw Medical Center Dallas
Department
Obstetrics & Gynecology
Type
Schools of Medicine
DUNS #
City
Dallas
State
TX
Country
United States
Zip Code
75390
Porter, J C; Ijames, C F; Wang, T C et al. (1995) Purification and identification of pituitary cytotropic factor. Proc Natl Acad Sci U S A 92:5351-5
Kedzierski, W; Aguila-Mansilla, N; Kozlowski, G P et al. (1994) Expression of tyrosine hydroxylase gene in cultured hypothalamic cells: roles of protein kinase A and C. J Neurochem 62:431-7
Aguila-Mansilla, N; Kedzierski, W; Porter, J C (1993) Localization of a defect in hypothalamic dopaminergic neurons of the aged brain that results in impaired PKA-dependent activation of tyrosine hydroxylase. J Pharmacol Exp Ther 267:171-5
Aguila-Mansilla, N; Jorquera, B A; Kedzierski, W et al. (1991) Effect of cerebroventricular anterior pituitary grafts on in situ expression of tyrosine hydroxylase in dopaminergic neurons of the aged animal. Endocrinology 128:1303-9
Kedzierski, W; Porter, J C (1991) A novel non-enzymatic procedure for removing DNA template from RNA transcription mixtures. Biotechniques 10:210-4
Aguila-Mansilla, N; Kedzierski, W; Porter, J C (1991) Testicular inhibition of tyrosine hydroxylase expression in tuberoinfundibular and nigrostriatal dopaminergic neurons. Endocrinology 129:877-82
Porter, J C; Aguila-Mansilla, N; Ramin, S M et al. (1991) Tyrosine hydroxylase expression in hypothalamic cells: analysis of the roles of adenosine 3',5'-monophosphate- and Ca2+/calmodulin-dependent protein kinases in the action of pituitary cytotropic factor. Endocrinology 129:2477-85
Kedzierski, W; Porter, J C (1990) Quantitative study of tyrosine hydroxylase mRNA in catecholaminergic neurons and adrenals during development and aging. Brain Res Mol Brain Res 7:45-51
Porter, J C; Kedzierski, W; Aguila-Mansilla, N et al. (1990) The tuberoinfundibular dopaminergic neurons of the brain: hormonal regulation. Adv Exp Med Biol 274:1-23
Gonzalez, H A; Kedzierski, W; Aguila-Mansilla, N et al. (1989) Hormonal control of tyrosine hydroxylase in the median eminence: demonstration of a central role for the pituitary gland. Endocrinology 124:2122-7

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