Askanas, Valerie; Engel, W King; Nogalska, Anna (2015) Sporadic inclusion-body myositis: A degenerative muscle disease associated with aging, impaired muscle protein homeostasis and abnormal mitophagy. Biochim Biophys Acta 1852:633-43
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Nogalska, Anna; D'Agostino, Carla; Engel, W King et al. (2015) Activation of the Unfolded Protein Response in Sporadic Inclusion-Body Myositis but Not in Hereditary GNE Inclusion-Body Myopathy. J Neuropathol Exp Neurol 74:538-46
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Askanas, Valerie; Engel, W King; Nogalska, Anna (2012) Pathogenic considerations in sporadic inclusion-body myositis, a degenerative muscle disease associated with aging and abnormalities of myoproteostasis. J Neuropathol Exp Neurol 71:680-93
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Nogalska, Anna; D'Agostino, Carla; Engel, W King et al. (2012) Activation of the ?-secretase complex and presence of ?-secretase-activating protein may contribute to A?42 production in sporadic inclusion-body myositis muscle fibers. Neurobiol Dis 48:141-9
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D'Agostino, C; Nogalska, A; Engel, W K et al. (2011) In sporadic inclusion body myositis muscle fibres TDP-43-positive inclusions are less frequent and robust than p62 inclusions, and are not associated with paired helical filaments. Neuropathol Appl Neurobiol 37:315-20
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Terracciano, Chiara; Nogalska, Anna; Engel, W King et al. (2010) In AbetaPP-overexpressing cultured human muscle fibers proteasome inhibition enhances phosphorylation of AbetaPP751 and GSK3beta activation: effects mitigated by lithium and apparently relevant to sporadic inclusion-body myositis. J Neurochem 112:389-96
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Nogalska, Anna; Engel, W King; Askanas, Valerie (2010) Increased BACE1 mRNA and noncoding BACE1-antisense transcript in sporadic inclusion-body myositis muscle fibers--possibly caused by endoplasmic reticulum stress. Neurosci Lett 474:140-3
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Nogalska, Anna; D'Agostino, Carla; Engel, W King et al. (2010) Decreased SIRT1 deacetylase activity in sporadic inclusion-body myositis muscle fibers. Neurobiol Aging 31:1637-48
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Nogalska, Anna; D'Agostino, Carla; Engel, W King et al. (2010) Novel demonstration of amyloid-? oligomers in sporadic inclusion-body myositis muscle fibers. Acta Neuropathol 120:661-6
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Nogalska, Anna; D'Agostino, Carla; Terracciano, Chiara et al. (2010) Impaired autophagy in sporadic inclusion-body myositis and in endoplasmic reticulum stress-provoked cultured human muscle fibers. Am J Pathol 177:1377-87
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