Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37AI016689-17
Application #
2060394
Study Section
Special Emphasis Panel (NSS)
Project Start
1980-06-01
Project End
1998-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
17
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Washington
Department
Pediatrics
Type
Schools of Medicine
DUNS #
135646524
City
Seattle
State
WA
Country
United States
Zip Code
98195
Muczynski, K A; Cotner, T; Anderson, S K (2001) Unusual expression of human lymphocyte antigen class II in normal renal microvascular endothelium. Kidney Int 59:488-97
Muczynski, K A; Anderson, S K; Pious, D (1998) Discoordinate surface expression of IFN-gamma-induced HLA class II proteins in nonprofessional antigen-presenting cells with absence of DM and class II colocalization. J Immunol 160:3207-16
Cotner, T; Pious, D (1995) HLA-DR beta chains enter into an aggregated complex containing GRP-78/BiP prior to their degradation by the pre-Golgi degradative pathway. J Biol Chem 270:2379-86
Cotner, T (1992) Unassembled HLA-DR beta monomers are degraded rapidly by a nonlysosomal mechanism. J Immunol 148:2163-8
Stimac, E; Urieli-Shoval, S; Kempin, S et al. (1991) Defective HLA DRA X box binding in the class II transactive transcription factor mutant 6.1.6 and in cell lines from class II immunodeficient patients. J Immunol 146:4398-405
Stimac, E; Lyons, S; Pious, D (1988) Transcription of HLA class II genes in the absence of B-cell-specific octamer-binding factor. Mol Cell Biol 8:3734-9
Levine, F; Erlich, H; Mach, B et al. (1985) Deletion mapping of HLA and chromosome 6p genes. Proc Natl Acad Sci U S A 82:3741-5
Levine, F; Pious, D (1985) Different roles for cytosine methylation in HLA class II gene expression. Immunogenetics 22:427-40
Pious, D; Dixon, L; Levine, F et al. (1985) HLA class II regulation and structure. Analysis with HLA-DR3 and HLA-DP point mutants. J Exp Med 162:1193-207
Levine, F; Erlich, H A; Mach, B et al. (1985) Transcriptional regulation of HLA class II and invariant chain genes. J Immunol 134:637-40