Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
4R37AI019807-21
Application #
6652370
Study Section
Special Emphasis Panel (NSS)
Program Officer
Mallia, Conrad M
Project Start
1983-05-01
Project End
2009-01-31
Budget Start
2004-02-15
Budget End
2005-01-31
Support Year
21
Fiscal Year
2004
Total Cost
$487,189
Indirect Cost
Name
Dana-Farber Cancer Institute
Department
Type
DUNS #
076580745
City
Boston
State
MA
Country
United States
Zip Code
02215
Reinherz, Ellis L; Wang, Jia-huai (2015) Codification of bidentate pMHC interaction with TCR and its co-receptor. Trends Immunol 36:300-6
Choi, Young I; Duke-Cohan, Jonathan S; Chen, Wei et al. (2014) Dynamic control of ?1 integrin adhesion by the plexinD1-sema3E axis. Proc Natl Acad Sci U S A 111:379-84
Choi, Young I; Duke-Cohan, Jonathan S; Tan, Jing et al. (2013) Plxnd1 expression in thymocytes regulates their intrathymic migration while that in thymic endothelium impacts medullary topology. Front Immunol 4:392
Wang, Jia-huai; Reinherz, Ellis L (2011) A new angle on TCR activation. Immunity 35:658-60
Touma, Maki; Keskin, Derin B; Shiroki, Fumiko et al. (2011) Impaired B cell development and function in the absence of IkappaBNS. J Immunol 187:3942-52
Kim, Sun Taek; Touma, Maki; Takeuchi, Koh et al. (2010) Distinctive CD3 heterodimeric ectodomain topologies maximize antigen-triggered activation of alpha beta T cell receptors. J Immunol 185:2951-9
Vernier, Gregory; Wang, Jie; Jennings, Laura D et al. (2009) Solubilization and characterization of the anthrax toxin pore in detergent micelles. Protein Sci 18:1882-95
Kim, Sun Taek; Takeuchi, Koh; Sun, Zhen-Yu J et al. (2009) The alphabeta T cell receptor is an anisotropic mechanosensor. J Biol Chem 284:31028-37
Choi, Young I; Duke-Cohan, Jonathan S; Ahmed, Wesam B et al. (2008) PlexinD1 glycoprotein controls migration of positively selected thymocytes into the medulla. Immunity 29:888-98
Takeuchi, Koh; Yang, Hailin; Ng, Elise et al. (2008) Structural and functional evidence that Nck interaction with CD3epsilon regulates T-cell receptor activity. J Mol Biol 380:704-16

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